SLUG Antibody (SNAI2)

  • Catalog number
    F47911-0.08ML
  • Price
    Please ask
  • Size
    0.08 ml
  • Category
    Antibody
  • Concentration
    In 1X PBS, pH 7.4, with 0.09% sodium azide
  • Form
    Purified
  • Conjugation
    Unconjugated
  • Clone
    Polyclonal antibody
  • Recognised antigen
    SLUG (SNAI2)
  • Host animal
    Rabbit (Oryctolagus cuniculus)
  • Clonality
    Polyclonal (rabbit origin)
  • Species reactivity
    Human (Homo sapiens), Mouse (Mus musculus) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
  • Tested applications
    WB, IHC, IF, ELISA
  • Recommended dilutions
    Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50
  • Notes
    Titration of the SLUG antibody may be required due to differences in protocols and secondary/substrate sensitivity.
  • Intented use
    This SLUG antibodyis to be used only for research purposes and not for diagnostics..
  • Uniprot
    O43623
  • Purity
    Purified
  • Description
    SLUG/SNAI2 is a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporadic cases of neural tube defects. [Wiki]
  • Immunogen
    A portion of amino acids 98-129 from human SNAI2 was used as the immunogen for this SLUG antibody.
  • Storage
    Aliquot the SLUG antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
  • Properties
    If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
    SLUG   SNAI2  
  • Gene symbol
    SNAI2
  • Short name
    Anti-SLUG (SNAI2)
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Isotype
    Rabbit Ig
  • Alternative name
    Antibodies to SLUG (SNAI2)
  • Alternative technique
    antibodies
Gene info
  • Identity
  • Gene
  • Long gene name
    snail family transcriptional repressor 2
  • Synonyms gene
  • Synonyms gene name
    • slug homolog, zinc finger protein (chicken)
    • snail homolog 2 (Drosophila)
    • snail family zinc finger 2
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1998-07-03
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Zinc fingers C2H2-type
    • SNAG transcriptional repressors
  • VEGA ID
  • Locus Specific Databases
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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