SirtACt for cell activation

SirtACt for cell activation is available 2 times from Biovision labs

2741-2 | SirtACt for cell activationsize: 2 mg | 177.65 USD

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2741-10 | SirtACt for cell activationsize: 10 mg | 531.78 USD

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  • Description
    SirtAct is a potent Sirtuin 1 (SIRT1) activator. It increases fluorescence by 233% in a SIRT1 activity assay. SIRT1 stimulation by SirtAct leads to decreased tissue factor mediated thrombogenicity in mice. It inhibits NF-κB activation and reduces inflammatory cytokine production in lamina propria mononuclear cells from IBD patients. SirtAct also prevents and cures experimental colitis in a mouse model.
  • Peptide sequence
    N/A
  • CAS number
    839699-72-8
  • Molecular weight
    367.5
  • Category
    Biochemicals
  • Other name
    2-​Amino-​N-​cyclopentyl-​1-​(3-​methoxypropyl)-​1H-​pyrrolo[2,​3-​b]quinoxaline-​3-​carboxamide; CAY10591; SIRT1 activator 3; Sirtuin1 Activator 3
  • Molecular formula
    C₂₀H₂₅N₅O₂
  • Physical appearance
    Olive green solid
  • Supplied with
    N/A
  • Is this a salt?
    No
  • Is it cell-permeable?
    Yes
  • Purification
    ≥98% by TLC
  • Reconstitute instructions
    DMSO (50 mg/ml) or EtOH (20 mg/ml, warm)
  • Storage condition
    -20°C
  • Shipping condition
    Gel Pack
  • Maximum time for storage
    36 months
  • Storage instructions
    Protect from air and light
  • Additional description
    For cells, cell lines and tissues in culture till half confluency.
  • Gene target
  • Short name
    SirtACt for activation
  • Technique
    activation
  • Alternative name
    SirtACt to measure cellular activation
  • Tissue
    cell
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