SIGLEC10 Antibody

• Catalog number
  bs-2706R
• Price
  Please ask
• Size
  0.1ml

• Long name
  SIGLEC10 Primary Polyclonal Antibody
• Also known as
  SIGLEC10 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  SIGLEC10
• Specificity
  This is a highly specific antibody against SIGLEC10.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Subcellular location
  Extracellular
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SIGLEC10
• Tested Applications
  WB, FCM, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), FCM(1:20-100), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  SIGLEC10 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. It preferentially binds to alpha2,3- or 2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. SIGLEC10 interacts with PTPN6/SHP-1 upon phosphorylation. The protein is expressed by peripheral blood leukocytes (eosinophils, monocytes and a natural killer cell subpopulation).
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  PRO940; mSiglec G; Sialic acid binding Ig like lectin 10; Sialic acid binding Ig like lectin 10; sialic acid binding Ig like lectin 10 Ig like lectin 7; sialic acid binding Ig like lectin G; Sialic acid binding Immunoglobulin like lectin 10; SIGLEC 10; Siglec G; siglec like gene 2; Siglec like protein 2; Siglec like protein 2; Siglecg; SLG2.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  SIGLEC10  
• Gene symbol
  SIGLEC10-AS1, SIGLEC10
• Short name
  Anti-SIGLEC10
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  SIGLEC10 Polyclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  sialic acid binding Ig-like lectin 10, SIGLEC10 and IDBG-65888 and ENSG00000142512 and 89790, protein binding, Extracellular

Gene info

• Identity
  HGNC:40719
• Gene
  SIGLEC10-AS1
• Long gene name
  SIGLEC10 antisense RNA 1
• Locus
  19q13.41
• Discovery year
  2020-03-20
• Entrez gene record
  100129083
• RefSeq identity
  • NR_164124
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:15620
• Gene
  SIGLEC10
• Long gene name
  sialic acid binding Ig like lectin 10
• Synonyms gene name
  • sialic acid binding Ig-like lectin 10
• Synonyms
  • SIGLEC-10
  • SLG2
  • PRO940
  • MGC126774
• Synonyms name
  • sialic acid binding Ig-like lectin 10 Ig-like lectin 7
  • siglec-like gene 2
• GenBank acession
  • AF310233
• Locus
  19q13.41
• Discovery year
  2001-06-29
• Entrez gene record
  89790
• Pubmed identfication
  • 11284738
• RefSeq identity
  • NM_033130
• Classification
  • C2-set domain containing
  • Sialic acid binding Ig like lectins
  • V-set domain containing
• VEGA ID
  OTTHUMG00000165521

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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