Sheep Polyclonal (IgG) to Human SERPINC1 / Antithrombin III

• Catalog number
  MBS244192
• Price
  Please ask
• Size
  0.05 mL

• Products_type
  Antibody
• Products_short_name
  [SERPINC1 / Antithrombin III]
• Products_name_syn
  [Anti-SERPINC1 / Antithrombin III Antibody IHC-plus; SERPINC1; Antithrombin III; Antithrombin-III; ATIII; AT3; Serpin C1; AT3D; THPH7; Human SERPINC1; Antithrombin III]
• Other_names
  [antithrombin-III; Antithrombin-III; antithrombin-III; serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1; serpin peptidase inhibitor, clade C (antithrombin), member 1; Serpin C1]
• Products_gene_name
  [SERPINC1]
• Other_gene_names
  [SERPINC1; SERPINC1; AT3; AT3D; ATIII; THPH7; AT3; ATIII]
• Clonality
  Polyclonal
• Reactivity
  Cat, Dog, Horse, Human, Mouse, Rat
• Specificity
  Recognizes human Antithrombin III (ATIII). Species cross-reactivity: Feline, canine, equine, mouse and rat. Does not react with chicken, bovine, porcine, guinea pig, goat, or rabbit. Reactivity against the sera of the listed species has been assessed by double diffusion using 10 ul of antisera against 1 ul of species sera.
• Purity
  Ion exchange Chromatography
• Form
  Glycine buffered saline, pH 7.4, 0.1% sodium azide, 0.1% EACA, 0.01% Benzamidine, 1 mM EDTA.
• Concentration
  11 mg/ml
• Storage_stability
  Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles.
• Tested_application
  Immunohistochemistry (IHC - Paraffin), Immunodiffusion, Immunoelectrophoresis
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• About
  Immunoglobulin gamma, IgG, mouse monoclonal H&L chain clones or rabbit, goat polyclonal antibodies have 4 parts. There are 2 heavy chains, 2 light chains. The IgG antibody has 2 antigen binding sites. They represent 70% or more of serum antibodies. This antibody can be antigen purified or protein A or G purified. For storage sodium azide is added or you can call us to request azide free antibody preparations. These will need colder storage temperatures. Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
• Group
  Polyclonals and antibodies

• Gene target
  SERPINC1   Antithrombin   III  
• Gene symbol
  SERPINC1, CPLX3, MGAT3, MGST3, P4HA3, CASP5, IGHVIII-82, THAP4, MT-CSB3, IGHVIII-44
• Short name
  Polyclonal (IgG) SERPINC1 / Antithrombin III
• Technique
  Polyclonal, IgG, IgGs, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Host
  Sheep
• Isotype
  IgG, IgG
• Species
  Human, Humans, The sheep (Ovis aries) ELISAs are detecting sheep proteins and antigens. Some epitopes will also recognize goat proteins. Sheep and goats are also used to produce polyclonals. An adult female sheep is referred to as a ewe a male as a ram, a castrated male as a wether, and a younger sheep as a lamb. Sheeps
• Alternative name
  ovine polyclonal (Immunoglobulin G) to H. sapiens SERPINC1 / Antithrombin III
• Alternative technique
  polyclonals, immunoglobulins

Gene info

• Identity
  HGNC:775
• Gene
  SERPINC1
• Long gene name
  serpin family C member 1
• Synonyms gene
  • AT3
• Synonyms gene name
  • serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1
  • serpin peptidase inhibitor, clade C (antithrombin), member 1
• Synonyms
  • ATIII
  • MGC22579
• Synonyms name
  • antithrombin III
  • signal peptide antithrombin part 1
  • coding sequence signal peptide antithrombin part 1
  • antithrombin (aa 375-432)
• GenBank acession
  • X68793
• Locus
  1q25.1
• Discovery year
  1986-01-01
• Entrez gene record
  462
• Pubmed identfication
  • 3979120
  • 24172014
• RefSeq identity
  • NM_000488
• Classification
  • Serpin peptidase inhibitors
• VEGA ID
  OTTHUMG00000037276
• Locus Specific Databases
  • Antithrombin III mutation database
  • LRG_577

Gene info

• Identity
  HGNC:27652
• Gene
  CPLX3
• Long gene name
  complexin 3
• Synonyms
  • CPX-III
• GenBank acession
  • BC018026
• Locus
  15q24.1
• Discovery year
  2005-08-02
• Entrez gene record
  594855
• Pubmed identfication
  • 15911881
• RefSeq identity
  • NM_001030005
• VEGA ID
  OTTHUMG00000142816

Gene info

• Identity
  HGNC:7046
• Gene
  MGAT3
• Long gene name
  beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase
• Synonyms gene name
  • mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
• Synonyms
  • GNT-III
• GenBank acession
  • D13789
• Locus
  22q13.1
• Discovery year
  1993-08-27
• Entrez gene record
  4248
• Pubmed identfication
  • 8370666
• RefSeq identity
  • NM_002409
• Classification
  • Mannosyl-glycoprotein N-acetylglucosaminyltransferases
• VEGA ID
  OTTHUMG00000030185

Gene info

• Identity
  HGNC:7064
• Gene
  MGST3
• Long gene name
  microsomal glutathione S-transferase 3
• Synonyms
  • GST-III
• Synonyms name
  • microsomal glutathione S-transferase III
  • microsomal GST-3
  • microsomal GST-III
• GenBank acession
  • AF026977
• Locus
  1q24.1
• Discovery year
  1997-10-16
• Entrez gene record
  4259
• Pubmed identfication
  • 9278457
• RefSeq identity
  • NM_004528
• Classification
  • Microsomal glutathione S-transferases
• VEGA ID
  OTTHUMG00000034627

Gene info

• Identity
  HGNC:30135
• Gene
  P4HA3
• Long gene name
  prolyl 4-hydroxylase subunit alpha 3
• Synonyms gene name
  • procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide III
  • prolyl 4-hydroxylase, alpha polypeptide III
• Synonyms
  • C-P4Halpha(III)
• Synonyms name
  • collagen prolyl 4-hydroxylase alpha(III)
• GenBank acession
  • AY327887
• Locus
  11q13.4
• Discovery year
  2004-05-12
• Entrez gene record
  283208
• Pubmed identfication
  • 14500733
• RefSeq identity
  • NM_182904
• VEGA ID
  OTTHUMG00000165254

Gene info

• Identity
  HGNC:1506
• Gene
  CASP5
• Long gene name
  caspase 5
• Synonyms gene name
  • caspase 5, apoptosis-related cysteine protease
  • caspase 5, apoptosis-related cysteine peptidase
• Synonyms
  • ICE(rel)III
• Locus
  11q22.3
• Discovery year
  1996-09-13
• Entrez gene record
  838
• Pubmed identfication
  • 7797592
  • 9250871
• RefSeq identity
  • NM_004347
• Classification
  • Caspases
  • Caspase recruitment domain containing
• VEGA ID
  OTTHUMG00000048073

Gene info

• Identity
  HGNC:5709
• Gene
  IGHVIII-82
• Long gene name
  immunoglobulin heavy variable (III)-82 (pseudogene)
• Synonyms gene name
  • immunoglobulin heavy variable (III)-82
  • immunoglobulin heavy variable (III)-82 pseudogene
• Synonyms
  • IGHV(III)-82
• GenBank acession
  • AB019437
• Locus
  14q32.33
• Discovery year
  2000-04-17
• Entrez gene record
  28338
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000151732

Gene info

• Identity
  HGNC:23187
• Gene
  THAP4
• Long gene name
  THAP domain containing 4
• Synonyms
  • CGI-36
  • Nb(III)
• Synonyms name
  • nitrobindin
• GenBank acession
  • AF258556
• Locus
  2q37.3
• Discovery year
  2003-10-08
• Entrez gene record
  51078
• Pubmed identfication
  • 12575992
  • 10810093
  • 30524950
• RefSeq identity
  • NM_015963
• Classification
  • THAP domain containing
• VEGA ID
  OTTHUMG00000133410

Gene info

• Identity
  HGNC:7426
• Gene
  MT-CSB3
• Long gene name
  mitochondrially encoded conserved sequence block III
• Synonyms gene
  • MTCSB3
• Synonyms gene name
  • conserved sequence block III
• Synonyms
  • CSB-III
• Locus
  mitochondria
• Discovery year
  1989-10-11
• Pubmed identfication
  • 2982153
• Classification
  • Mitochondrially encoded regions

Gene info

• Identity
  HGNC:5700
• Gene
  IGHVIII-44
• Long gene name
  immunoglobulin heavy variable (III)-44 (pseudogene)
• Synonyms gene name
  • immunoglobulin heavy variable (III)-44
  • immunoglobulin heavy variable (III)-44 pseudogene
• Synonyms
  • IGHV(III)-44
• GenBank acession
  • M99673
• Locus
  14q32.33
• Discovery year
  2000-04-17
• Entrez gene record
  28345
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000152065

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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