SERPINB2 Antibody

• Catalog number
  R31768
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  SERPINB2
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC-P
• Recommended dilutions
  Western blot: 0.5-1ug/ml,IHC (Paraffin): 0.5-1ug/ml
• Notes
  The stated application concentrations are suggested starting amounts. Titration of the SERPINB2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This SERPINB2 antibodyis to be used only for research purposes and not for diagnostics..
• Gene ID
  5055
• Purity
  Antigen affinity
• Description
  SERPINB2 is also known as PAI or PAI2. It is a coagulation factor that inactivates tPA and Urokinase. It is present in most cells, especially monocytes/macrophages. The protein exists in two forms, a 60-kDa extracellular glycosylated form and a 43-kDa intracellular form. It is present only at detectable quantities in blood during pregnancy, as it is produced by the placenta, and may explain partially the increased rate of thrombosisduring pregnancy. The majority of expressed SERPINB2 remains unsecreted due to the presence of an inefficient internal signal peptide.
• Immunogen
  Human partial recombinant protein (AA 1-180) was used as the immunogen for this SERPINB2 antibody.
• Storage
  After reconstitution, the SERPINB2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  SERPINB2  
• Gene symbol
  SERPINB2
• Short name
  Anti-SERPINB2
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to SERPINB2
• Alternative technique
  antibodies
• Alternative to gene target
  serpin peptidase inhibitor, clade B (ovalbumin), member 2, HsT1201 and PAI and PAI-2 and PAI2 and PLANH2, SERPINB2 and IDBG-4558 and ENSG00000197632 and 5055, serine-type endopeptidase inhibitor activity, Extracellular, Serpinb2 and IDBG-186363 and ENSMUSG00000062345 and 18788

Gene info

• Identity
  HGNC:8584
• Gene
  SERPINB2
• Long gene name
  serpin family B member 2
• Synonyms gene
  • PLANH2
  • PAI2
• Synonyms gene name
  • serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 2
  • serpin peptidase inhibitor, clade B (ovalbumin), member 2
• Synonyms
  • HsT1201
  • PAI-2
• Synonyms name
  • plasminogen-activator inhibitor
• GenBank acession
  • Y00630
• Locus
  18q21.33-q22.1
• Discovery year
  1989-02-07
• Entrez gene record
  5055
• Pubmed identfication
  • 24172014
• RefSeq identity
  • NM_002575
• Classification
  • Serpin peptidase inhibitors
• VEGA ID
  OTTHUMG00000060592

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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