Semagacestat
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Catalog numberS255600
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PricePlease ask
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Size1 mg
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Chemical available in other sizesPlease inquire size and price
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Stock availabilityIn Stock
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Cas number425386-60-3
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Chemical s molecular weight361.44
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Chemical s main applicationsSemagacestat is an inhibitor of the γ-secretase enzyme. γ-Secretase enzyme is pivotal in the generation of β-amyloid (Aβ), a neurotoxic endogenous peptide believed to be involved in the pathogenesis of Alzheimer's disease (AD).
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Chemical s categoryHeterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals,
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Other name(2S)-2-Hydroxy-3-methyl-N-[(1S)-1-methyl-2-oxo-2-[[(1S)-2,3,4,5-tetrahydro-3-methyl-2-oxo-1H-3-benzazepin-1-yl]amino]ethyl]butanamide; LY 450139;
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Chemical s formulaC19H27N3O4
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Physical propertiesWhite Solid
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Melting temperature213-215°C
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Boiling temperatureNo Data Available
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Chemical s soluble inDMSO (Slightly), Dichloromethane (Slightly), Methanol (Slightly)
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Stability conditionsNo Data Available
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Storage-20˚C Freezer
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Gene target
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Short nameSemagacestat
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Alternative nameSemagacestat
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