Semagacestat

  • Catalog number
    S255600
  • Price
    Please ask
  • Size
    1 mg
  • Chemical available in other sizes
    Please inquire size and price
  • Stock availability
    In Stock
  • Cas number
    425386-60-3
  • Chemical s molecular weight
    361.44
  • Chemical s main applications
    Semagacestat is an inhibitor of the γ-secretase enzyme. γ-Secretase enzyme is pivotal in the generation of β-amyloid (Aβ), a neurotoxic endogenous peptide believed to be involved in the pathogenesis of Alzheimer's disease (AD).
  • Chemical s category
    Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals,
  • Other name
    (2S)-2-Hydroxy-3-methyl-N-[(1S)-1-methyl-2-oxo-2-[[(1S)-2,3,4,5-tetrahydro-3-methyl-2-oxo-1H-3-benzazepin-1-yl]amino]ethyl]butanamide; LY 450139;
  • Chemical s formula
    C19H27N3O4
  • Physical properties
    White Solid
  • Melting temperature
    213-215°C
  • Boiling temperature
    No Data Available
  • Chemical s soluble in
    DMSO (Slightly), Dichloromethane (Slightly), Methanol (Slightly)
  • Stability conditions
    No Data Available
  • Storage
    -20˚C Freezer
  • Gene target
  • Short name
    Semagacestat
  • Alternative name
    Semagacestat
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