Sema4C Antibody
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Catalog numberbs-1123R
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PricePlease ask
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Size0.1ml
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Long nameSema4C Primary Polyclonal Antibody
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Also known asSema4C PAb
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CategoryPrimary Antibodies
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ConjugationUnconjugated
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Target AntigenSema4C
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SpecificityThis is a highly specific antibody against Sema4C.
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Modification sNone
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Modification site sUnmodified antibody
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ClonalityPolyclonal antibody
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Clone numberPolyclonal antibody
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Concentration1ug per 1ul
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Subcellular locationCytoplasm
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SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Sema4C
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Gene ID number9037
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Swiss ProtQ13591
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Tested ApplicationsWB, IHC-P, IF(IHC-P)
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Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
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Cross reactivityHuman, Mouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigenBifunctional axonal guidance cue regulated by sulfated proteoglycans; attractive effects result from interactions with heparan sulfate proteoglycans (HSPGs), while the inhibitory effects depend on interactions with chondroitin sulfate proteoglycans (CSPGs) (By similarity). Ligand for receptor PLXNB3. In glioma cells, SEMA5A stimulation of PLXNB3 results in the disassembly of F-actin stress fibers, disruption of focal adhesions and cellular collapse as well as inhibition of cell migration and invasion through ARHGDIA-mediated inactivation of RAC1. May promote angiogenesis by increasing endothelial cell proliferation and migration and inhibiting apoptosis.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym namessemF; SEMAF; Semaphorin-5A; Semaphorin-F; Sema F; SEMA5A
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PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolSEMA4C
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Short nameAnti-Sema4C
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TechniqueAntibody, antibodies against human proteins, antibodies for
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HostRabbit (Oryctolagus cuniculus)
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IsotypeImmunoglobulin G (IgG)
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Alternative nameSema4C Polyclonal Antibody
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Alternative techniqueantibodies
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Alternative to gene targetsema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C, SEMA4C and IDBG-62124 and ENSG00000168758 and 54910, protein binding, Extracellular, Sema4c and IDBG-144779 and ENSMUSG00000026121 and 20353, SEMA4C and IDBG-629784 and ENSBTAG00000021920 and 526028
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Gene info
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Identity
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Gene
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Long gene namesemaphorin 4C
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Synonyms gene
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Synonyms gene name
- sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2004-02-04
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Immunoglobulin like domain containing
- Semaphorins
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data