Anti-FOXP3 Antibody

• Catalog number
  F46753-0.4ML
• Price
  Please ask
• Size
  0.4 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  Anti-FOXP3
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, ELISA
• Recommended dilutions
  Western blot: 1:1000
• Notes
  Titration of the anti-FOXP3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This anti-FOXP3 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  Q9BZS1
• Purity
  Antigen affinity
• Description
  Forkhead box P3 is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
• Immunogen
  A portion of amino acids 397-423 from the human protein was used as the immunogen for this anti-FOXP3 antibody.
• Storage
  Aliquot the anti-FOXP3 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Additional description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Gene
  Forkhead Box Protein P3 scurfin FOXP3, is a protein involved in immune system responses. A member of the FOX protein family, FOXP3 appears to function as a master regulator of the regulatory pathway in the development and function of regulatory T cells. Foxp3 or forkhead box P3 or skurfin or scurfin or skurfina is also known as IPEX, AIID, PIDX, XPID and DIETER.
• French translation
  anticorps

• Gene target
  FOXP3  
• Gene symbol
  FOXP3
• Short name
  Anti-Anti-FOXP3
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to Anti-FOXP3
• Alternative technique
  antibodies
• Alternative to gene target
  forkhead box P3, FOXP3 and IDBG-66215 and ENSG00000049768 and 50943, NFAT protein binding, nuclei, Foxp3 and IDBG-128986 and ENSMUSG00000039521 and 20371, FOXP3 and IDBG-637186 and ENSBTAG00000013279 and 506053

Gene info

• Identity
  HGNC:6106
• Gene
  FOXP3
• Long gene name
  forkhead box P3
• Synonyms gene
  • IPEX
• Synonyms gene name
  • immune dysregulation, polyendocrinopathy, enteropathy, X-linked
• Synonyms
  • JM2
  • XPID
  • AIID
  • PIDX
  • DIETER
  • SCURFIN
• Locus
  Xp11.23
• Discovery year
  2000-05-05
• Entrez gene record
  50943
• Pubmed identfication
  • 10677306
  • 11138001
• RefSeq identity
  • NM_014009
• Classification
  • Forkhead boxes
• VEGA ID
  OTTHUMG00000024135
• Locus Specific Databases
  • FOXP3base: Mutation registry for Immunodysregulation, polyendocrinopathy, and enteropathy, X-linked; IPEX
  • Global Variome shared LOVD
  • LRG_62

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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