SCN1B Antibody

• Catalog number
  R30346
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  SCN1B
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB
• Recommended dilutions
  Western blot: 0.5-1ug/ml
• Notes
  The stated application concentrations are suggested starting amounts. Titration of the SCN1B antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This SCN1B antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  Q07699
• Purity
  Antigen affinity
• Description
  Voltage-gated sodium(Na+) channels are essential for the generation and propagation of action potentials in striated muscle and neuronal tissues. The complete coding region of Sodium channel, voltage-gated, beta 1(SCN1B) is found in approximately 9.0 kb of genomic DNA and consists of five exons(72 to 749 bp) and four introns(90 bp to 5.5 kb). It is mapped to 19q13.1 and can act as a candidate gene for hereditary disorders affecting membrane excitability. Sodium channel beta1 subunits play important roles in the regulation of sodium channel density and localization and are involved in axo-glial communication at nodes of Ranvier.
• Immunogen
  An amino acid sequence from the N-terminus of human SCN1B (YENEVLQLEEDERFEGRVVWNGS) was used as the immunogen for this SCN1B antibody (100% homologous in human, mouse and rat).
• Storage
  After reconstitution, the SCN1B antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  SCN1B  
• Gene symbol
  SCN1B
• Short name
  Anti-SCN1B
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to SCN1B
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:10586
• Gene
  SCN1B
• Long gene name
  sodium voltage-gated channel beta subunit 1
• Synonyms gene name
  • sodium channel, voltage-gated, type I, beta polypeptide
  • sodium channel, voltage-gated, type I, beta
  • sodium channel, voltage-gated, type I, beta subunit
  • sodium channel, voltage gated, type I beta subunit
• Locus
  19q13.11
• Discovery year
  1990-05-14
• Entrez gene record
  6324
• Pubmed identfication
  • 8394762
• Classification
  • Sodium voltage-gated channel beta subunits
  • V-set domain containing
• VEGA ID
  OTTHUMG00000182472
• Locus Specific Databases
  • LRG_420

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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