SBI 0206965 for cell activation

SBI 0206965 for cell activation is available 2 times from Biovision labs

9580-25 | SBI-0206965 for cell activationsize: 25 mg | 669.79 USD

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9580-5 | SBI-0206965 for cell activationsize: 5 mg | 211.87 USD

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  • Description
    SBI-0206965 is a potent, selective and cell permeable autophagy kinase ULK1 inhibitor. It inhibits ULK1 kinase with IC₅₀ of 108 nM and the highly related kinase ULK2 with IC₅₀ of 711 nM. SBI-0206965 suppresses ULK1-mediated phosphorylation events in cells, regulating autophagy and cell survival. SBI-0206965 greatly synergizes with mechanistic target of rapamycin (mTOR) inhibitors to kill tumor cells.
  • Peptide sequence
    N/A
  • CAS number
    N/A
  • Molecular weight
    489.33
  • Category
    Biochemicals
  • Other name
    2-((5-bromo-2-((3,4,5-trimethoxyphenyl)amino)pyrimidin-4-yl)oxy)-N-methylbenzamide
  • Molecular formula
    C₂₁H₂₁BrN₄O₅
  • Physical appearance
    Off-white solid
  • Supplied with
    N/A
  • Is this a salt?
    No
  • Is it cell-permeable?
    Yes
  • Purification
    ≥98% by HPLC
  • Reconstitute instructions
    DMSO >20 mg/ml)
  • Storage condition
    -20°C
  • Shipping condition
    gel pack
  • Maximum time for storage
    36 months
  • Storage instructions
    Protect from air and light
  • Additional description
    For cells, cell lines and tissues in culture till half confluency.
  • Gene target
  • Short name
    SBI-0206965 for activation
  • Technique
    activation
  • Alternative name
    SBI-0206965 to measure cellular activation
  • Tissue
    cell
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