Salinomycin Sodium

  • Catalog number
    B1584-25
  • Price
    Please ask
  • Size
    25 mg
  • Alternative_name
    (R)-2-((2R,5S,6R)-6-((2S,3S,4S,6R)-6-((2S,5S,7R,9S,10S,12R,15R)-2-((2R,5R,6S)-5-ethyl-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)-15-hydroxy-2,10,12-trimethyl-1,6,8-trioxadispiro[4.1.57.35]pentadec-13-en-9-yl)-3-hydroxy-4-methyl-5-oxooctan-2-yl)-5-
  • Description
    Salinomycin is a polyether ionophore antibiotic that has recently been identified as an antitumor drug for several types of cancer stem cell (CSC) treatments. Salinomycin inhibits the migration and invasion of liver cancer stem cells (LCSCs) through the dephosphorylated FAK and ERK1/2 pathways.
  • CAS Number
    55721-31-8
  • Structure Available
    Yes
  • Molecular Formula
    C₄₂H₆₉O₁₁. Na
  • Molecular Weight
    772.98
  • Cell Permeable
    yes
  • Purity
    ≥850U/mg
  • Solubilities
    DMSO (~5 mg/ml)
  • Handling
    Protect from air and moisture
  • Tag Line
    A cancer stem cell inhibitor
  • Storage Condition
    -20°C
  • Shipping Condition
    Gel Pack
  • Shelf Life
    36 months
  • MDL Number
    MFCD00036900
  • PubChem CID
    23703990
  • SMILES
    CCC(C1CCC(C(O1)C(C)C(C(C)C(=O)C(CC)C2C(CC(C3(O2)C=CC(C4(O3)CCC(O4)(C)C5CCC(C(O5)C)(CC)O)O)C)C)O)C)C(=O)[O-].[Na+]
  • InChi
    InChI=1S/C42H70O11.Na/c1-11-29(38(46)47)31-15-14-23(4)36(50-31)27(8)34(44)26(7)35(45)30(12-2)37-24(5)22-25(6)41(51-37)19-16-32(43)42(53-41)21-20-39(10,52-42)33-17-18-40(48,13-3)28(9)49-33;/h16,19,23-34,36-37,43-44,48H,11-15,17-18,20-22H2,1-10H3,(H,46,47);/q;+1/p-1/t23-,24-,25+,26-,27-,28-,29+,30-,31+,32+,33+,34+,36+,37-,39-,40+,41-,42-;/m0./s1
  • InChi Key
    YPZYGIQXBGHDBH-UZHRAPRISA-M
  • MSDS Available
    Yes
  • Gene target
  • Short name
    Salinomycin Sodium
  • Alternative name
    Salinomycin Sodium
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