7-Ethyl-10-(4-amino-1-piperidino)carbonyloxycamptothecin Dihydrochloride
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Catalog numberE899155
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PricePlease ask
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Size1 mg
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Chemical available in other sizesPlease inquire size and price
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Stock availabilityIn Stock
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Cas numberThis product doesn't have CAS Number
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Chemical s molecular weight591.48
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Chemical s main applications7-Ethyl-10-(4-amino-1-piperidino)carbonyloxycamptothecin is a major metabolite of Irinotecan (I767500, HCl trihydrate), a DNA topoisomerase inhibitor.
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Other name4-Amino-(4S)-4,11-diethyl-3,4,12,14-tetrahydro -4-hydroxy-3,14-dioxo-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl 1-Piperidinecarboxylic Acid Ester Dihydrochloride; RPR 132595A Dihydrochloride; NPC (metabolite) Dihydrochloride
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Chemical s formulaC28H32Cl2N4O6
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Physical propertiesYellowish Orange Solid
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Melting temperature>125°C (dec.)
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Boiling temperatureNo Data Available
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Chemical s soluble inDMSO, Methanol
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Stability conditionsHygroscopic
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StorageAmber Vial, -86°C Freezer, Under inert atmosphere
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Gene target
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Gene symbolIGHVII-1-1, MIR1-1, TRUND-NNN8-1, TRUND-NNN7-1, IGKV1OR2-1, MIR101-1, MIR1289-1, MIR16-1, PIRC1
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Short name7-Ethyl-10-(4-amino-1-piperidino)carbonyloxycamptothecin Dihydrochloride
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Alternative name7-Ethyl-10-(4-amino-1-piperidino)carbonyloxycamptothecin Dihydrochloride
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Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin heavy variable (II)-1-1 (pseudogene)
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Synonyms gene name
- immunoglobulin heavy variable (II)-1-1
- immunoglobulin heavy variable (II)-1-1 pseudogene
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-04-17
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Entrez gene record
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RefSeq identity
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Classification
- Immunoglobulin heavy locus at 14q32.33
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemicroRNA 1-1
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Synonyms gene
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Synonyms
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Locus
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Discovery year2004-04-23
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR1/206 family
Gene info
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Identity
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Gene
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Long gene nametRNA-undetermined (NNN) 8-1
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Synonyms gene name
- transfer RNA-undetermined (NNN) 8-1
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GenBank acession
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Locus
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Discovery year2014-06-20
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Entrez gene record
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Pubmed identfication
Gene info
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Identity
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Gene
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Long gene nametRNA-undetermined (NNN) 7-1
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Synonyms gene name
- transfer RNA-undetermined (NNN) 7-1
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GenBank acession
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Locus
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Discovery year2014-06-20
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Entrez gene record
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Pubmed identfication
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin kappa variable 1/OR2-1 (pseudogene)
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Synonyms gene
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Synonyms gene name
- immunoglobulin kappa variable 1/OR-1
- immunoglobulin kappa variable 1/OR-1 pseudogene
- immunoglobulin kappa variable 1/OR-1 (pseudogene)
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-04-18
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Entrez gene record
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Pubmed identfication
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Classification
- Immunoglobulin kappa (IGK) orphons
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemicroRNA 101-1
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Synonyms gene
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Synonyms
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Locus
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Discovery year2004-04-23
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR101 family
Gene info
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Identity
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Gene
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Long gene namemicroRNA 1289-1
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Synonyms gene
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Synonyms
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Locus
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Discovery year2008-11-03
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR1289 family
Gene info
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Identity
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Gene
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Long gene namemicroRNA 16-1
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Synonyms gene
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Synonyms
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Locus
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Discovery year2004-04-23
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR15/16 family
Gene info
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Identity
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Gene
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Long gene namepiwi-interacting RNA cluster 1
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Locus
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Discovery year2009-11-05
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Entrez gene record
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Pubmed identfication
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Classification
- Piwi-interacting RNA clusters
MeSH Data
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Name
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ConceptScope note: The insertion of recombinant DNA molecules from prokaryotic and/or eukaryotic sources into a replicating vehicle, such as a plasmid or virus vector, and the introduction of the resultant hybrid molecules into recipient cells without altering the viability of those cells.
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Tree numbers
- E05.393.220
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Qualifiersdrug effects, methods, radiation effects