S-2-Methoxyacetoxymethyl-Salubrinal Hydrobromide

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Cas number

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Chemical s molecular weight

662.81
Chemical s main applications

S-2-Methoxyacetoxymethyl-Salubrinal hydrobromide is a hydrobromide salt analogue of Salubrinal (S100550), a phosphatase inhibitor that protects cells from apoptosis caused by endoplasmic reticulum stress and is now known to induce and facilitate apoptotic death of leukemic cell lines.
Chemical s category

Amines, Apoptosis, Aromatics, Drug Analogues, Heterocycles, Inhibitors, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
Chemical s formula

C25H24BrCl3N4O4S
Physical properties

No Data Available
Melting temperature

No Data Available
Boiling temperature

No Data Available
Chemical s soluble in

No Data Available
Stability conditions

No Data Available
Storage

No Data Available
Chemical s specifications

Gene target

S-2-Methoxyacetoxymethyl-Salubrinal Hydrobromide
Gene symbol

RPS2, B3GAT2, PSMD2, HLA-S, CTSL3P, STRN3, BNIPL, TNFAIP8, CENPS, MRPS7
Short name

S-2-Methoxyacetoxymethyl-Salubrinal Hydrobromide
Alternative name

S-2-Methoxyacetoxymethyl-Salubrinal Hydrobromide

Identity

HGNC:10404
Gene

RPS2
Long gene name

ribosomal protein S2
Synonyms
- LLREP3
- S2
GenBank acession
- AB007147
Locus

16p13.3
Discovery year

1998-07-29
Entrez gene record

6187
Pubmed identfication
- 9582194
RefSeq identity
- NM_002952
Classification
- Small nucleolar RNA protein coding host genes
- S ribosomal proteins
VEGA ID

OTTHUMG00000128708

Identity

HGNC:922
Gene

B3GAT2
Long gene name

beta-1,3-glucuronyltransferase 2
Synonyms
- GlcAT-S
Synonyms name
- glucuronosyltransferase S
- galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2
GenBank acession
- AB075843
Locus

6q13
Discovery year

2000-01-07
Entrez gene record

135152
Pubmed identfication
- 12383500
RefSeq identity
- NM_080742
Classification
- Beta-1,3-glucuronyltransferases
VEGA ID

OTTHUMG00000014997

Identity

HGNC:9559
Gene

PSMD2
Long gene name

proteasome 26S subunit ubiquitin receptor, non-ATPase 2
Synonyms gene name
- proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
- proteasome 26S subunit, non-ATPase 2
Synonyms
- S2
- P97
- TRAP2
- MGC14274
- Rpn1
GenBank acession
- AK095245
Locus

3q27.1
Discovery year

1995-11-28
Entrez gene record

5708
Pubmed identfication
- 8774743
RefSeq identity
- NM_002808
Classification
- Proteasome
- Armadillo like helical domain containing
VEGA ID

OTTHUMG00000156796

Identity

HGNC:15720
Gene

STRN3
Long gene name

striatin 3
Synonyms gene name
- striatin, calmodulin binding protein 3
Synonyms
- SG2NA
- PPP2R6B
- S/G2NA
Synonyms name
- cell cycle S/G2 nuclear autoantigen
- protein phosphatase 2 regulatory subunit B'''beta
Locus

14q12
Discovery year

2002-07-22
Entrez gene record

29966
Pubmed identfication
- 7864889
- 10681496
RefSeq identity
- NM_014574
Classification
- WD repeat domain containing
- STRIPAK complex
- Protein phosphatase 2 regulatory subunits
- MicroRNA protein coding host genes
VEGA ID

OTTHUMG00000140201

Identity

HGNC:23163
Gene

CENPS
Long gene name

centromere protein S
Synonyms gene
- APITD1
- MHF1
Synonyms gene name
- apoptosis-inducing, TAF9-like domain 1
- FANCM associated histone fold protein 1
Synonyms
- CENP-S
- FAAP16
GenBank acession
- BC029430
Locus

1p36.22
Discovery year

2003-09-25
Entrez gene record

378708
Pubmed identfication
RefSeq identity
- NM_199294
Classification
- Constitutive centromere associated network
VEGA ID

OTTHUMG00000059085