Ruxolitinib,JAK kinase inhibitor
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Catalog number
SIH-509-5MG
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Price
Please ask
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Size
5 mg
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Research Area s
Cell Signaling , Cancer , Apoptosis , Cancer Growth Inhibitors , Tyrosine Kinase Inhibitors
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Category
Small Molecules
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Product Type
Inhibitor
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CAS No
941678-49-5
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MolecularFormula
C17H18N6
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Molecular Weight
306.4
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Purity
>98%
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Solubility
Soluble in DMSO (25 mg/ml) or EtOH (~15 mg/ml)
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Appearance
Off-white solid
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Storage Temperature
-20°C
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Shipping Temperature
Shipped Ambient
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Description
Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
Gene info
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Identity
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Gene
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Long gene name
Janus kinase 3
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1994-12-19
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Jak family tyrosine kinases
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VEGA ID
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Locus Specific Databases
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