Picropodophyllotoxin,IGF1R inhibitor

• Catalog number
  SIH-467-25MG
• Price
  Please ask
• Size
  25 mg

• Research Area s
  Cell Signaling
• Category
  Small Molecules
• Product Type
  Inhibitor
• CAS No
  477-47-4
• MolecularFormula
  C22H22O8
• Molecular Weight
  414.4
• Purity
  ≥96% (HPLC)
• Solubility
  Soluble in DMSO (10 mg/ml, warm) or dimethyl formamide (25 mg/ml)
• Appearance
  White solid
• Storage Temperature
  -20°C
• Shipping Temperature
  Shipped Ambient
• Description
  Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.

• Gene target
  Picropodophyllotoxin   IGF1R   inhibitor  
• Gene symbol
  IRAIN, IGF1R
• Short name
  Picropodophyllotoxin IGF1R inhibitor
• Alternative name
  Picropodophyllotoxin,insulin-like growth factor 1 receptor suppressor
• Alternative to gene target
  insulin-like growth factor 1 receptor, CD221 and IGFIR and IGFR and JTK13, IGF1R and IDBG-31432 and ENSG00000140443 and 3480, transferase activity, Cell surfaces, Igf1r and IDBG-192339 and ENSMUSG00000005533 and 16001, IGF1R and IDBG-628659 and ENSBTAG00000021527 and 281848

Gene info

• Identity
  HGNC:50365
• Gene
  IRAIN
• Long gene name
  IGF1R antisense imprinted non-protein coding RNA
• Synonyms
  • IGF1R-AS
• Synonyms name
  • IGF1R antisense RNA
• Locus
  15q26.3
• Discovery year
  2014-08-07
• Entrez gene record
  104472848
• Pubmed identfication
  • 25092925
  • 27644252
• RefSeq identity
  • NR_126453
• Classification
  • Long non-coding RNAs with non-systematic symbols
• Locus Specific Databases
  • LRG_1064

Gene info

• Identity
  HGNC:5465
• Gene
  IGF1R
• Long gene name
  insulin like growth factor 1 receptor
• Synonyms gene name
  • insulin-like growth factor 1 receptor
• Synonyms
  • JTK13
  • CD221
  • IGFIR
  • MGC18216
  • IGFR
• GenBank acession
  • M69229
• Locus
  15q26.3
• Discovery year
  1988-07-07
• Entrez gene record
  3480
• Pubmed identfication
  • 1316909
• RefSeq identity
  • NM_000875
• Classification
  • Receptor tyrosine kinases
  • Fibronectin type III domain containing
  • CD molecules
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000149851
• Locus Specific Databases
  • Global Variome shared LOVD
  • LRG_1055

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