Rabbit Anti Human ROBO1 Antibody-Non-conjugated
-
Catalog numberCSB-PA896760LA01HU_50ug
-
PricePlease ask
-
Size50ug
-
-
Long nameRabbit Antibody against Human ROBO1, Non-conjugated
-
Synonym nameROBO1 Human Antibody
-
Species reactivityHuman
-
Tested applications recommended dilutionsELISA,WB,IF;Recommended dilution:WB:1:500-1:5000,IF:1:50-1:200
-
ConjugationNon-conjugated
-
Antibody isotypeIgG
-
UniProt IDQ9Y6N7
-
FormatLiquid, diluted in buffer
-
Buffer compositionPreservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
-
Purity>95%
-
Purification methodProtein G purified
-
Antibody categoryPolyclonal Antibodies
-
Immunogen typeRecombinant Human Roundabout homolog 1 protein (29-143AA)
-
Immunogen speciesHuman
-
AliasRoundabout homolog 1,Deleted in U twenty twenty,H-Robo-1,ROBO1,DUTT1
-
BackgroundReceptor for SLIT1 and SLIT2 that mediates cellular responses to molecular guidance cues in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development (PubMed:10102268, PubMed:24560577). Interaction with the intracellular domain of FLRT3 mediates axon attraction towards cells expressing NTN1 (PubMed:24560577). In axon growth cones, the silencing of the attractive effect of NTN1 by SLIT2 may require the formation of a ROBO1-DCC complex (By similarity). Plays a role in the regulation of cell migration via its interaction with MYO9B; inhibits MYO9B-mediated stimulation of RHOA GTPase activity, and thereby leads to increased levels of active, GTP-bound RHOA (PubMed:26529257). May be required for lung development (By similarity).
-
ClonalityPolyclonal antibody
-
Shipping and storageROBO1 Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
-
Short name of the antigenRoundabout homolog 1
-
DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
-
PropertiesIf you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
-
AboutRabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
-
Latin nameOryctolagus cuniculus
-
French translationanticorps
-
Gene target
-
Gene symbolROBO1
-
Short nameAnti-ROBO1
-
Techniqueanti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for, antibody Conjugates
-
HostRabbit, Rabbits
-
SpeciesHuman, Humans
-
Alternative nameROBO1 Antibody
-
Alternative techniqueantibodies, rabbit-anti
-
Alternative to gene targetroundabout, axon guidance receptor, homolog 1 (Drosophila), DUTT1 and SAX3, ROBO1 and IDBG-45469 and ENSG00000169855 and 6091, protein heterodimerization activity, Cell surfaces, Robo1 and IDBG-171072 and ENSMUSG00000022883 and 19876, ROBO1 and IDBG-630648 and ENSBTAG00000009851 and 536815
-
Gene info
-
Identity
-
Gene
-
Long gene nameroundabout guidance receptor 1
-
Synonyms gene name
- roundabout (axon guidance receptor, Drosophila) homolog 1
- roundabout, axon guidance receptor, homolog 1 (Drosophila)
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1998-03-26
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Fibronectin type III domain containing
- Ig-like cell adhesion molecule family
- I-set domain containing
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data