Ro 106-9920-d5
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Catalog numberR637502
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PricePlease ask
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Size1 mg
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Chemical available in other sizesPlease inquire size and price
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Stock availabilityPlease Inquire
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Cas numberThis product doesn't have CAS Number
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Chemical s molecular weight250.29
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Chemical s main applicationsLabelled Ro 106-9920 (R637500). Ro 106-9920 is an inhibitor of NF-κB activation, possibly via selective inhibition of LPS- and TNF-α-induced IκBα ubiquitination (IC50 = 3 μM). Ro 106-9920 blocks subsequent production of TNF-α, IL-1β and IL-6. Inhibits mucin production in an in vitro model of COPD, and is anti-inflammatory following oral administration in vivo. Also weakly inhibits EGFR, 5-lipoxygenase and iNOS.
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Chemical s categoryAromatics, Heterocycles, Inhibitors, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
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Other name6-[(Phenyl-d5)sulfinyl]tetrazolo[1,5-b]pyridazine;
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Chemical s formulaC10H2D5N5OS
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Physical propertiesNo Data Available
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Melting temperatureNo Data Available
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Boiling temperatureNo Data Available
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Chemical s soluble inNo Data Available
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Stability conditionsNo Data Available
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StorageNo Data Available
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Gene target
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Gene symbolPRELID1, OR8C1P
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Short nameRo 106-9920-d5
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Alternative nameRo 106-9920-d5
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Gene info
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Identity
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Gene
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Long gene namePRELI domain containing 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2007-02-20
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- PRELI domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameolfactory receptor family 8 subfamily C member 1 pseudogene
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Synonyms gene
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Synonyms gene name
- olfactory receptor, family 8, subfamily C, member 1 pseudogene
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-11-09
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Entrez gene record
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Pubmed identfication
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Classification
- Olfactory receptors, family 8
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VEGA ID