Ro 106-9920-d5

  • Catalog number
    R637502
  • Price
    Please ask
  • Size
    1 mg
  • Chemical available in other sizes
    Please inquire size and price
  • Stock availability
    Please Inquire
  • Cas number
    This product doesn't have CAS Number
  • Chemical s molecular weight
    250.29
  • Chemical s main applications
    Labelled Ro 106-9920 (R637500). Ro 106-9920 is an inhibitor of NF-κB activation, possibly via selective inhibition of LPS- and TNF-α-induced IκBα ubiquitination (IC50 = 3 μM). Ro 106-9920 blocks subsequent production of TNF-α, IL-1β and IL-6. Inhibits mucin production in an in vitro model of COPD, and is anti-inflammatory following oral administration in vivo. Also weakly inhibits EGFR, 5-lipoxygenase and iNOS.
  • Chemical s category
    Aromatics, Heterocycles, Inhibitors, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
  • Other name
    6-[(Phenyl-d5)sulfinyl]tetrazolo[1,5-b]pyridazine;
  • Chemical s formula
    C10H2D5N5OS
  • Physical properties
    No Data Available
  • Melting temperature
    No Data Available
  • Boiling temperature
    No Data Available
  • Chemical s soluble in
    No Data Available
  • Stability conditions
    No Data Available
  • Storage
    No Data Available
  • Gene target
  • Gene symbol
    PRELID1, OR8C1P
  • Short name
    Ro 106-9920-d5
  • Alternative name
    Ro 106-9920-d5
Gene info
Gene info
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