Clonality Polyclonal antibody
Immunogen species Human
Antibody category Polyclonal Antibodies
Background E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination, endocytosis and subsequent degradation of Wnt receptor complex components Frizzled. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone.
Short name of the antigen E3 ubiquitin-protein ligase RNF43
Synonym name RNF43 Human Antibody
Antibody isotype IgG
Shipping and storage RNF43 Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
Purification method Protein G purified
Format Liquid, diluted in buffer
UniProt ID Q68DV7
Alias E3 ubiquitin-protein ligase RNF43, RING finger protein 43, RING-type E3 ubiquitin transferase RNF43, RNF43
Species reactivity Human
Buffer composition Preservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Immunogen type Recombinant Human E3 ubiquitin-protein ligase RNF43 protein (566-697AA)
Properties If you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation anticorps
Short name RNF43 Antibody
Alternative name RNF43 (Antibody to)
Alternative technique antibodies