Prickle Antibody

• Catalog number
  bs-12411R
• Price
  Please ask
• Size
  0.1ml

• Long name
  Prickle Primary Polyclonal Antibody
• Also known as
  Prickle PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  Prickle
• Specificity
  This is a highly specific antibody against Prickle.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Prickle
• Gene ID number
  144165
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Prickle1 is an 831 amino acid protein that contains one PET domain and three LIM zinc-binding domains and localizes to the cytoplasm, as well as to the nuclear membrane. Expressed at higher levels in placenta and at lower levels in liver, brain, kidney, lung and pancreas, Prickle1 is thought to function as a nuclear receptor that interacts with NRSF, a silencer protein that binds the DNA sequence element NRSE (neuron-restrictive silencer element). Defects in the gene encoding Prickle1 are associated with autosomal recessive progressive myoclonic epilepsy-1B, which is characterized by quick jerks of the arms, shoulders or legs. The gene encoding Prickle1 maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  FLJ31627; FLJ31937; MGC138902; MGC138903; EPM1B; Prickle 1; Prickle homolog 1 Drosophila; Prickle like protein 1; Prickle-like 1; Prickle1; REST-Interacting LIM Domain Protein; REST/NRSF interacting LIM domain protein 1; RILP; PRIC1_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Prickle  
• Gene symbol
  PRICKLE2, PRICKLE3, PRICKLE1
• Short name
  Anti-Prickle
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  Prickle Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:20340
• Gene
  PRICKLE2
• Long gene name
  prickle planar cell polarity protein 2
• Synonyms gene name
  • prickle-like 2 (Drosophila)
  • prickle homolog 2 (Drosophila)
• Synonyms
  • DKFZp686D143
• GenBank acession
  • AK127839
• Locus
  3p14.1
• Discovery year
  2003-02-10
• Entrez gene record
  166336
• Pubmed identfication
  • 12525887
• RefSeq identity
  • NM_198859
• Classification
  • LIM domain containing
  • Prickle planar cell polarity proteins
• VEGA ID
  OTTHUMG00000158789

Gene info

• Identity
  HGNC:6645
• Gene
  PRICKLE3
• Long gene name
  prickle planar cell polarity protein 3
• Synonyms gene
  • LMO6
• Synonyms gene name
  • LIM domain only 6
  • prickle homolog 3 (Drosophila)
• GenBank acession
  • BC016856
• Locus
  Xp11.23
• Discovery year
  1997-04-21
• Entrez gene record
  4007
• Pubmed identfication
  • 9344658
• RefSeq identity
  • NM_006150
• Classification
  • LIM domain containing
  • Prickle planar cell polarity proteins
• VEGA ID
  OTTHUMG00000024134
• Locus Specific Databases
  • Global Variome shared LOVD

Gene info

• Identity
  HGNC:17019
• Gene
  PRICKLE1
• Long gene name
  prickle planar cell polarity protein 1
• Synonyms gene name
  • prickle-like 1 (Drosophila)
  • prickle homolog 1 (Drosophila)
• Synonyms
  • FLJ31937
  • EPM1B
  • RILP
• Synonyms name
  • REST/NRSF interacting LIM domain protein
• GenBank acession
  • AK056499
• Locus
  12q12
• Discovery year
  2003-02-10
• Entrez gene record
  144165
• Pubmed identfication
  • 12525887
  • 18976727
• Classification
  • LIM domain containing
  • Prickle planar cell polarity proteins
• VEGA ID
  OTTHUMG00000169443

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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