PDZ RHOGEF/GTRAP48 Antibody

• Catalog number
  bs-10157R
• Price
  Please ask
• Size
  0.1ml

• Long name
  PDZ RHOGEF/GTRAP48 Primary Polyclonal Antibody
• Also known as
  PDZ RHOGEF/GTRAP48 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  PDZ RHOGEF/GTRAP48
• Specificity
  This is a highly specific antibody against PDZ RHOGEF/GTRAP48.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Subcellular location
  Cytoplasm
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PDZ RHOGEF/GTRAP48
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008].
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  PDZ-RhoGEF; ARHGB_HUMAN; ARHGEF 11; ARHGEF11; DKFZp667F1223; Glutamate transporter EAAT4 associated protein 48; GTRAP 48; GTRAP48; PDZ RhoGEF; Rho guanine exchange factor GEF 11; Rho guanine nucleotide exchange factor GEF 11; Rho guanine nucleotide exchange factor 11; RhoA specic guanine nucleotide exchange factor; RhoGEF glutamate transport modulator.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  PDZ   RHOGEF/GTRAP48  
• Gene symbol
  ARHGEF11, ARHGEF17, ARHGEF1, RGS3, ARHGEF15, ARHGEF18, RAPGEF6, RAPGEF2, USH1C
• Short name
  Anti-PDZ RHOGEF/GTRAP48
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  PDZ RHOGEF/GTRAP48 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:14580
• Gene
  ARHGEF11
• Long gene name
  Rho guanine nucleotide exchange factor 11
• Synonyms gene name
  • Rho guanine nucleotide exchange factor (GEF) 11
• Synonyms
  • KIAA0380
  • GTRAP48
  • PDZ-RHOGEF
• GenBank acession
  • AB002378
• Locus
  1q23.1
• Discovery year
  2001-02-08
• Entrez gene record
  9826
• Pubmed identfication
  • 10526156
  • 9205841
• RefSeq identity
  • NM_198236
• Classification
  • PDZ domain containing
  • Dbl family Rho GEFs
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000041292

Gene info

• Identity
  HGNC:21726
• Gene
  ARHGEF17
• Long gene name
  Rho guanine nucleotide exchange factor 17
• Synonyms gene name
  • Rho guanine nucleotide exchange factor (GEF) 17
• Synonyms
  • TEM4
  • KIAA0337
  • p164-RhoGEF
• Synonyms name
  • Rho-specific guanine-nucleotide exchange factor 164 kDa
  • tumor endothelial marker 4
• GenBank acession
  • AF378754
• Locus
  11q13.4
• Discovery year
  2003-09-25
• Entrez gene record
  9828
• Pubmed identfication
  • 11559528
  • 12071859
• RefSeq identity
  • NM_014786
• Classification
  • Dbl family Rho GEFs
• VEGA ID
  OTTHUMG00000167971

Gene info

• Identity
  HGNC:681
• Gene
  ARHGEF1
• Long gene name
  Rho guanine nucleotide exchange factor 1
• Synonyms gene name
  • Rho guanine nucleotide exchange factor (GEF) 1
• Synonyms
  • P115-RHOGEF
  • SUB1.5
  • LBCL2
• GenBank acession
  • U64105
• Locus
  19q13.2
• Discovery year
  2000-03-10
• Entrez gene record
  9138
• Pubmed identfication
  • 8810315
  • 9135076
• RefSeq identity
  • NM_199002
• Classification
  • Dbl family Rho GEFs
• VEGA ID
  OTTHUMG00000182679

Gene info

• Identity
  HGNC:9999
• Gene
  RGS3
• Long gene name
  regulator of G protein signaling 3
• Synonyms gene name
  • regulator of G-protein signalling 3
  • regulator of G-protein signaling 3
• Synonyms
  • C2PA
  • FLJ20370
  • PDZ-RGS3
• GenBank acession
  • AF006610
• Locus
  9q32
• Discovery year
  1997-06-09
• Entrez gene record
  5998
• Pubmed identfication
  • 8602223
  • 11034339
• RefSeq identity
  • NM_017790
• Classification
  • Regulators of G-protein signaling
  • C2 domain containing
  • PDZ domain containing
• VEGA ID
  OTTHUMG00000021048

Gene info

• Identity
  HGNC:15590
• Gene
  ARHGEF15
• Long gene name
  Rho guanine nucleotide exchange factor 15
• Synonyms gene name
  • Rho guanine nucleotide exchange factor (GEF) 15
• Synonyms
  • KIAA0915
  • Vsm-RhoGEF
  • ARGEF15
  • FLJ13791
  • MGC44868
• Synonyms name
  • Rho guanine exchange factor (GEF) 15
  • ephexin5
• GenBank acession
  • AB020722
• Locus
  17p13.1
• Discovery year
  2001-04-26
• Entrez gene record
  22899
• Pubmed identfication
  • 10048485
• RefSeq identity
  • NM_173728
• Classification
  • Dbl family Rho GEFs
• VEGA ID
  OTTHUMG00000108187

Gene info

• Identity
  HGNC:17090
• Gene
  ARHGEF18
• Long gene name
  Rho/Rac guanine nucleotide exchange factor 18
• Synonyms gene name
  • rho/rac guanine nucleotide exchange factor (GEF) 18
  • Rho/Rac guanine nucleotide exchange factor (GEF) 18
• Synonyms
  • P114-RhoGEF
  • KIAA0521
  • MGC15913
  • p114RhoGEF
• Synonyms name
  • Rho-specific guanine nucleotide exchange factor p114
• GenBank acession
  • AK074372
• Locus
  19p13.2
• Discovery year
  2004-01-09
• Entrez gene record
  23370
• Pubmed identfication
  • 9628581
  • 11318610
• RefSeq identity
  • NM_015318
• Classification
  • Dbl family Rho GEFs
  • Pleckstrin homology domain containing
• VEGA ID
  OTTHUMG00000177342

Gene info

• Identity
  HGNC:20655
• Gene
  RAPGEF6
• Long gene name
  Rap guanine nucleotide exchange factor 6
• Synonyms gene
  • PDZGEF2
• Synonyms gene name
  • PDZ domain containing guanine nucleotide exchange factor (GEF) 2
  • Rap guanine nucleotide exchange factor (GEF) 6
• Synonyms
  • RA-GEF-2
  • PDZ-GEF2
• GenBank acession
  • AF117947
• Locus
  5q31.1
• Discovery year
  2003-09-03
• Entrez gene record
  51735
• Pubmed identfication
  • 11524421
  • 12095257
• RefSeq identity
  • NM_016340
• Classification
  • PDZ domain containing
• VEGA ID
  OTTHUMG00000162683

Gene info

• Identity
  HGNC:16854
• Gene
  RAPGEF2
• Long gene name
  Rap guanine nucleotide exchange factor 2
• Synonyms gene
  • PDZGEF1
• Synonyms gene name
  • PDZ domain containing guanine nucleotide exchange factor (GEF) 1
  • Rap guanine nucleotide exchange factor (GEF) 2
• Synonyms
  • PDZ-GEF1
  • RA-GEF
  • DKFZP586O1422
  • KIAA0313
• Synonyms name
  • Rap GEP
• GenBank acession
  • AB002311
• Locus
  4q32.1
• Discovery year
  2003-05-20
• Entrez gene record
  9693
• Pubmed identfication
  • 9205841
  • 10934204
• RefSeq identity
  • NM_014247
• Classification
  • MicroRNA protein coding host genes
  • PDZ domain containing
• VEGA ID
  OTTHUMG00000161451

Gene info

• Identity
  HGNC:12597
• Gene
  USH1C
• Long gene name
  USH1 protein network component harmonin
• Synonyms gene
  • DFNB18
• Synonyms gene name
  • deafness, autosomal recessive 18
  • Usher syndrome 1C (autosomal recessive, severe)
  • Usher syndrome 1C
• Synonyms
  • PDZ73
  • harmonin
  • NY-CO-37
  • NY-CO-38
  • PDZ-73
  • AIE-75
  • PDZD7C
• Synonyms name
  • harmonin
• GenBank acession
  • AB006955
• Locus
  11p15.1
• Discovery year
  1992-06-08
• Entrez gene record
  10083
• Pubmed identfication
  • 10973247
  • 12107438
• RefSeq identity
  • NM_005709
• Classification
  • PDZ domain containing
• VEGA ID
  OTTHUMG00000166323
• Locus Specific Databases
  • Mutations of the Harmonin Gene
  • CCHMC-BMI & UC Hearing Loss Mutation Database

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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