RGS14 Antibody

  • Catalog number
    R31283
  • Price
    Please ask
  • Size
    0.1mg
  • Category
    Antibody
  • Concentration
    0.5mg/ml if reconstituted with 0.2ml sterile DI water
  • Form
    Antigen affinity purified
  • Conjugation
    Unconjugated
  • Clone
    Polyclonal antibody
  • Recognised antigen
    RGS14
  • Host animal
    Rabbit (Oryctolagus cuniculus)
  • Clonality
    Polyclonal (rabbit origin)
  • Species reactivity
    Human (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
  • Tested applications
    WB
  • Recommended dilutions
    Western blot: 0.5-1ug/ml
  • Notes
    The stated application concentrations are suggested starting amounts. Titration of the RGS14 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
  • Intented use
    This RGS14 antibodyis to be used only for research purposes and not for diagnostics..
  • Uniprot
    O43566
  • Purity
    Antigen affinity
  • Description
    Regulator of G-protein signaling 14 is a protein that in humans is encoded by the RGS14 gene. This gene encodes a member of the regulator of G-protein signaling family. By genomic sequence analysis, this gene is mapped to chromosome 5q35.3. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein(GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.
  • Immunogen
    An amino acid sequence from the C-terminus of human Regulator of G-protein signaling 14 (CTVLADQEVRLENR) was used as the immunogen for this RGS14 antibody (100% homologous in human, mouse and rat).
  • Storage
    After reconstitution, the RGS14 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
  • Properties
    If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
    RGS14  
  • Gene symbol
    RGS14, RGS16
  • Short name
    Anti-RGS14
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Isotype
    Rabbit IgG
  • Alternative name
    Antibodies to RGS14
  • Alternative technique
    antibodies
Gene info
  • Identity
  • Gene
  • Long gene name
    regulator of G protein signaling 14
  • Synonyms gene name
    • regulator of G-protein signalling 14
    • regulator of G-protein signaling 14
  • GenBank acession
  • Locus
  • Discovery year
    1999-07-06
  • Entrez gene record
  • RefSeq identity
  • Classification
    • Regulators of G-protein signaling
  • VEGA ID
Gene info
  • Identity
  • Gene
  • Long gene name
    regulator of G protein signaling 16
  • Synonyms gene name
    • regulator of G-protein signalling 16
    • regulator of G-protein signaling 16
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1998-03-17
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Regulators of G-protein signaling
  • VEGA ID
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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