Reverse Triiodothyronine Protein (OVA)

  • Catalog number
    abx165813
  • Price
    Please ask
  • Size
    50 μg
  • Category
    Proteins And Peptides
  • Clonality
    N/A
  • Raised in
    N/A
  • Target
    Reverse Triiodothyronine Protein
  • Immunogen
    see included datasheet or contact us
  • Species reactivity
    Human, Mouse, Rat (for other species please inquire)
  • Purification
    Affinity purified
  • Applications
    WB (for other applications please contact us)
  • Stock availability
    Shipped within 5-12 working days.
  • Storage conditions
    Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
  • Footnote
    This product is for research use only.
  • Gene
    Ovalbumin (abbreviated OVA) is the main protein found in egg white, making up 60-65% of the total protein. Ovalbumin displays sequence and three-dimensional homology to the serpin superfamily, but unlike most serpins it is not a serine protease inhibitor. The function of ovalbumin is unknown, although it is presumed to be a storage protein. OVA is also the best characterized and the first antigen proteins used as a transgene to make transgenic mice. Many different transgenic mouse models have systemic OVA expression driven by the ubiquitously expressed b-actin promoter or tissue-specific OVA expression with insulin promoter to drive the transgene expression, for studying type I diabetes, or in different isoforms, secreted or cell-membrane associated, and more recently as inducible transgene models. These C57BL/6 mice, BALB/c mice models are well characterized, and have contributed to our understanding of immunogenicity and tolerance by the OVA model.
  • Description
    Reverse transcription primers are used in PCR but in vivo reverse transcription begins when the viral particle that enters the cytoplasm of a target cell with its reverse transcriptase. The viral RNA genome enters the cytoplasm as part of a nucleoprotein complex that has not been well characterized. The process of reverse transcription generates, in the cytoplasm, a linear DNA via an intricate series of steps. This DNA is collinear with its RNA template, but it contains terminal duplications known as the long terminal repeats (LTRs) that are not present in viral RNA . Extant models for reverse transcription propose that two specialized template switches known as strand-transfer reactions or “jumps” are required to generate the LTRs.
  • Goup
    reverse transcription
  • Gene target
  • Short name
    Reverse Triiodothyronine Protein (OVA)
  • Technique
    reverse
  • Label
    OVA
  • Alternative name
    Reverse Triiodothyronine Protein (OVA)
  • Alternative technique
    transctription
MeSH Data
  • Name
  • Concept
    Scope note: A variation of the PCR technique in which cDNA is made from RNA via reverse transcription. The resultant cDNA is then amplified using standard PCR protocols.
  • Tree numbers
    • E05.393.620.500.725
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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