Retinoblastoma Antibody

  • Catalog number
    F51209-0.4ML
  • Price
    Please ask
  • Size
    0.4 ml
  • Category
    Antibody
  • Concentration
    In 1X PBS, pH 7.4, with 0.09% sodium azide
  • Form
    Purified
  • Conjugation
    Unconjugated
  • Clone
    Polyclonal antibody
  • Recognised antigen
    Retinoblastoma
  • Host animal
    Rabbit (Oryctolagus cuniculus)
  • Clonality
    Polyclonal (rabbit origin)
  • Species reactivity
    Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
  • Tested applications
    WB, IHC, FACS, ELISA
  • Recommended dilutions
    Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50
  • Notes
    Titration of the Retinoblastoma antibody may be required due to differences in protocols and secondary/substrate sensitivity.
  • Intented use
    This Retinoblastoma antibodyis to be used only for research purposes and not for diagnostics..
  • Uniprot
    P06400
  • Purity
    Purified
  • Description
    RB1/Retinoblastoma is a negative regulator of the cell cycle and was the first tumor suppressor gene found. This protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1.
  • Immunogen
    A portion of amino acids 858-886 from the human protein was used as the immunogen for this Retinoblastoma antibody.
  • Storage
    Aliquot the Retinoblastoma antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
  • Properties
    If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
  • Gene symbol
    RBBP7, RBBP4, RBBP9
  • Short name
    Anti-Retinoblastoma
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Isotype
    Rabbit Ig
  • Alternative name
    Antibodies to Retinoblastoma
  • Alternative technique
    antibodies
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    RB binding protein 4, chromatin remodeling factor
  • Synonyms gene name
    • retinoblastoma-binding protein 4
    • retinoblastoma binding protein 4
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1995-05-05
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • EMSY complex
    • SIN3 histone deacetylase complex subunits
    • WD repeat domain containing
    • NuRD complex subunits
    • Polycomb repressive complex 2
    • NURF complex
  • VEGA ID
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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