Rekombinant Human Urokinase (PLAU) (Recombinant Protein)
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Catalog number
33 100 103
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Price
Please ask
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Size
100 µg
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Protein type
Recombinant
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Protein subtype
EC 3.4.21.73
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Protein family
Kinase
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Protein description
PLAU specifically cleaves the zymogen plasminogen to form the active enzyme plasmin.
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Research area interests
Diseases associated with PLAU include Quebec Platelet Disorder and Alzheimer Disease. Among its related pathways are Wnt Signaling Pathway (WikiPathways) and Integrin Pathway.
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Package form
liquid
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Tested applications
Screening of inhibitors for Urokinase; Characterization of structure and function;
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Other names
PLAU, Plasminogen Activator, Urokinase; U-Plasminogen Activator
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Peptide sequence
MRALLARLLLCVLVVSDSKGSNELHQVPSNCDCLNGGTCVSNKYFSNIHWCNCPKKFGGQHCEIDKSKTCYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHRSDALQLGLGKHNYCRNPDNRRRPWCYVQVGLKPLVQECMVHDCADGKKPSSPPEELKFQCGQKTLRPRFKIIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIVYLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQTICLPSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTKMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWIRSHTKEENGLAL
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Available target modification
No
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Expression system
E.coli
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Product Subtype
protein fragment
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Active form
Yes
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Tag
untagged
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Contents
50 mM Tris-HCl pH 7.0, 100 mM NaCl, 0.05% NaN3
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Protein purity
>95%
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Molecular weight
47 kDa
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UniProt number
P00749
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Gene number
5328
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Abbreviation
PLAU
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Full name
plasminogen activator, urokinase
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Other desciption
Rekombinant human Urokinase expressed in E.coli without the signal peptide, Gene name: PLAU; Gene Alias: ATF,UPA, URK, u-PA, GenBank Accession # BC013575, Swiss Prot P00749. It appears as a major protein of about 47 kDa and represents more than 95 % of total protein.
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Purification
Mentioned in the data sheet
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PubMed citations
See the data sheet
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Warnings
For Research Use only.
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Shipping conditions
dry ice
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Storage condition
Store at -70°C
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Technical datasheet
Contact us to receive the datasheet
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
PLAU
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Short name
Rekombinant Urokinase (PLAU) (Recombinant Protein)
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Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. biotez advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Species
Homo sapiens, Humans
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Alternative name
Rekombinant H. sapiens Urokinase (plasminogen activator, urokinase) (Rec. Protein)
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Alternative technique
rec
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Alternative to gene target
plasminogen activator, urokinase, ATF and BDPLT5 and QPD and u-PA and UPA and URK, PLAU and IDBG-78889 and ENSG00000122861 and 5328, protein binding, Extracellular, Plau and IDBG-136606 and ENSMUSG00000021822 and 18792, PLAU and IDBG-630603 and ENSBTAG00000005947 and 281408
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Gene info
MeSH Data
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Name
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Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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