Recombinant Rat Niemann-Pick C1-like protein 1 (Npc1l1), partial

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About

Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
Latin name

Rattus norvegicus
Source

Recombinants or rec. proteins
Group

recombinants

Gene target

Niemann-Pick C1-like protein Npc1l1 partial
Gene symbol

SNAR-C1, TRGC1, PFDN4, TNS2, ARHGAP4, MAGEC1, SERPING1, PLAAT1
Short name

Recombinant Niemann-Pick C1-like protein 1 (Npc1l1), partial
Technique

Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
Host

Rat
Species

Rat, Rats
Alternative name

Rec. Rat Niemann-Pick C1-like protein 1 (Npc1l1), partial
Alternative technique

rec

Identity

HGNC:19737
Gene

TNS2
Long gene name

tensin 2
Synonyms gene
- TENC1
Synonyms gene name
- tensin like C1 domain-containing phosphatase
- tensin like C1 domain containing phosphatase (tensin 2)
Synonyms
- KIAA1075
- C1-TEN
GenBank acession
- AF518729
Locus

12q13.13
Discovery year

2002-12-09
Entrez gene record

23371
RefSeq identity
- NM_170754
Classification
- PTEN protein phosphatases
- SH2 domain containing
- C2 tensin-type domain containing
- MicroRNA protein coding host genes
VEGA ID

OTTHUMG00000169730

Identity

HGNC:674
Gene

ARHGAP4
Long gene name

Rho GTPase activating protein 4
Synonyms
- KIAA0131
- C1
- p115
- RhoGAP4
- SrGAP4
Synonyms name
- Rho-GAP hematopoietic protein C1
GenBank acession
- X78817
Locus

Xq28
Discovery year

1997-08-28
Entrez gene record

393
Pubmed identfication
- 8570618
RefSeq identity
- NM_001666
Classification
- AH/BAR family Rho GTPase activating proteins
- F-BAR domain containing
VEGA ID

OTTHUMG00000024226
Locus Specific Databases
- Global Variome shared LOVD

Identity

HGNC:1228
Gene

SERPING1
Long gene name

serpin family G member 1
Synonyms gene
- C1NH
Synonyms gene name
- serine (or cysteine) proteinase inhibitor, clade G (C1 inhibitor), member 1, (angioedema, hereditary)
- serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
Synonyms
- C1IN
- C1-INH
- HAE1
- HAE2
- C1INH
Synonyms name
GenBank acession
- X54486
Locus

11q12.1
Discovery year

2001-06-22
Entrez gene record

710
Pubmed identfication
- 2026152
- 24172014
RefSeq identity
- NM_000062
Classification
- Complement system regulators and receptors
- Serpin peptidase inhibitors
VEGA ID

OTTHUMG00000150304
Locus Specific Databases
- SERPING1base: Mutation registry for Hereditary angioedema
- LRG_105

Name

Primary Cell Culture
Concept

Scope note: The initial culturing of cells derived directly from fresh TISSUES.
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data