Recombinant Mouse Periostin / POSTN Protein (His tag) 100µg

  • Catalog number
    PKSM040677-100µg
  • Price
    Please ask
  • Size
    100µg
  • Activity
    Measured by its ability to induce adhesion of ATDC5 mouse chondrogenic cells.When cells are added to POSTN-His coated plates (10 μg/mL, 100 μL/well), approximately >40% will adhere specifically after 30 minutes at 37℃.
  • Synonym
    A630052E07Rik;AI747096;OSF-2;Osf2;peri;PLF;PN
  • Sequence
    Met 1-Gln 811
  • Fusion tag
    C-His
  • Accession
    NP_056599.1
  • Expressed Host
    HEK293 Cells
  • Shipping
    In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
  • Purity
    > 92 % as determined by SDS-PAGE
  • Endotoxin
    < 1.0 EU per μg of the protein as determined by the LAL method
  • Stability and Storage
    Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Mol Mass
    89 kDa
  • AP Mol Mass
    80-85 kDa
  • Formulation
    Lyophilized from sterile PBS, pH 7.4
  • Background
    Periostin ( POSTN ), also known as OSF2 (osteoblast specific factor 2), is a heterofunctional secreted extracellular matrix (ECM) protein comprised of four fasciclin domains that promotes cellular adhesion and movement, as well as collagen fibrillogenesis. Postn is expressed in unique growth centers during embryonic development where it facilitates epithelial-mesenchymal transition (EMT) of select cell populations undergoing reorganization. In the adult, Postn expression is specifically induced in areas of tissue injury or areas with ongoing cellular re-organization. In the adult heart Postn is induced in the ventricles following myocardial infarction, pressure overload stimulation, or generalized cardiomyopathy. Although the detailed function of Postn is still unclear, Postn-integrin interaction is thought to be involved in tumor development. Postn is frequently overexpressed in various types of human cancers, stimulating metastatic growth by promoting cancer cell survival, invasion and angiogenesis, and can be a useful marker to predict the behavior of cancer.
  • Conjugation
    histidine
  • Test
    Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
  • Latin name
    Mus musculus
  • Source
    Recombinants or rec. proteins
  • Group
    recombinants
  • Gene target
    Periostin   POSTN   Protein   His   tag   100µg  
  • Gene symbol
    POSTN
  • Short name
    Recombinant Mouse Periostin / POSTN Protein (His tag) 100µg
  • Technique
    Recombinant, Mouse, mouses, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
  • Host
    mouse
  • Label
    His
  • Species
    Mouse, Mouses
  • Alternative name
    Rec. Mouse Periostin / periostin, osteoblast specific factor Protein (histidine detection labelled) 100µg
  • Alternative technique
    rec, murine
  • Alternative to gene target
    periostin, osteoblast specific factor, OSF-2 and OSF2 and PDLPOSTN and periostin and PN, POSTN and IDBG-24971 and ENSG00000133110 and 10631, heparin binding, Extracellular, Postn and IDBG-144426 and ENSMUSG00000027750 and 50706, POSTN and IDBG-629835 and ENSBTAG00000012409 and 281960
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: The initial culturing of cells derived directly from fresh TISSUES.
  • Tree numbers
    • E01.370.225.500.223.500
    • E05.200.500.265.500
    • E05.242.223.500
    • E05.481.500.249.500
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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