Recombinant Mouse NKG2A / NKG2 / CD159A / KLRC1 Protein (His tag) 50µg
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Catalog numberPKSM040461-50µg
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PricePlease ask
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Size50µg
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ActivityNA
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SynonymCD159a;NKG2A;NKG2B
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SequenceAla94-Ile244
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Fusion tagN-His
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AccessionAAD24969.1
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Expressed HostHEK293 Cells
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ShippingIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
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Purity> 95 % as determined by SDS-PAGE
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Endotoxin< 1.0 EU per μg of the protein as determined by the LAL method
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Stability and StorageSamples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Mol Mass19.6 kDa
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AP Mol Mass33-40 kDa
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FormulationLyophilized from sterile PBS, pH 7.4
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BackgroundNKG2, also known as NKG2A(CD159A), is a member of the killer cell lectin-like receptor family. This family is a group of transmembrane proteins preferentially expressed in NK cells. Members of this fmaily are characterized by the type II membrane orientation and the presence of a C-type lectin domain. NKG2 contains 1 C-type lectin domain and forms a complex with another family member, KLRD1/CD94. It is expressed only in NK-cells, but not in T-cells or B-cells. It has been shown that NKG2 represents a family of related cDNA clones, designated NKG2A, NKG2B, NKG2C, and NKG2D, which encode type 2 integral membrane proteins (extracellular C-terminus) containing a C-type lectin domain. Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NKG2 functions as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.
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Conjugationhistidine
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TestMouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin nameMus musculus
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SourceRecombinants or rec. proteins
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Grouprecombinants
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Gene target
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Gene symbolKLRC1, KLRC4, KLRC3, KLRC2, KLRK1
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Short nameRecombinant Mouse NKG2A / NKG2 / CD159A / KLRC1 Protein (His tag) 50µg
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TechniqueRecombinant, Mouse, mouses, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
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Hostmouse
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LabelHis
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SpeciesMouse, Mouses
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Alternative nameRec. Mouse NKG2A / NKG2 / CD159A / KLRC1 Protein (histidine detection labelled) 50µg
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Alternative techniquerec, murine
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Gene info
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Identity
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Gene
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Long gene namekiller cell lectin like receptor C1
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Synonyms gene
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Synonyms gene name
- killer cell lectin-like receptor subfamily C, member 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1998-01-16
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- C-type lectin domain containing
- CD molecules
- Killer cell lectin like receptors
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namekiller cell lectin like receptor C4
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Synonyms gene name
- killer cell lectin-like receptor subfamily C, member 4
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-09-03
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Killer cell lectin like receptors
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namekiller cell lectin like receptor C3
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Synonyms gene name
- killer cell lectin-like receptor subfamily C, member 3
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-01-16
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- C-type lectin domain containing
- Killer cell lectin like receptors
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namekiller cell lectin like receptor C2
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Synonyms gene name
- killer cell lectin-like receptor subfamily C, member 2
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1998-01-16
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Entrez gene record
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Pubmed identfication
-
RefSeq identity
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Classification
- Killer cell lectin like receptors
- C-type lectin domain containing
- CD molecules
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namekiller cell lectin like receptor K1
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Synonyms gene
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Synonyms gene name
- DNA segment on chromosome 12 (unique) 2489 expressed sequence
- killer cell lectin-like receptor subfamily K, member 1
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Synonyms
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GenBank acession
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Locus
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Discovery year2003-12-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Killer cell lectin like receptors
- C-type lectin domain containing
- CD molecules
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VEGA ID
MeSH Data
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Name
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ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
