Recombinant Mouse JAM-A / F11R Protein (Fc tag)(Fc tag)

  • Catalog number
    PKSM040670-50µg
  • Price
    Please ask
  • Size
    50µg
  • Synonym
    9130004G24;AA638916;ESTM33;JAM;JAM-1;JAM-A;Jcam;Jcam1;Ly106
  • Activity
    NA
  • Sequence
    Met 1-Ala 242
  • Fusion tag
    C-Fc
  • Accession
    NP_766235.1
  • Expressed Host
    HEK293 Cells
  • Shipping
    In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
  • Purity
    > 94 % as determined by SDS-PAGE
  • Endotoxin
    < 1.0 EU per μg of the protein as determined by the LAL method
  • Stability and Storage
    Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Mol Mass
    50.2 kDa
  • AP Mol Mass
    57 kDa
  • Formulation
    Lyophilized from sterile PBS, pH 7.4
  • Background
    Junctional adhesion molecule-A (JAM-A), also known as F11 receptor (F11R) or Cluster of Differentiation 321 (CD321), is a transmembrane protein expressed at tight junctions of epithelial and endothelial cells, as well as on circulating leukocytes. JAM-A protein serves as a serotype-independent receptor for mammalian orthoreoviruses (reoviruses). It is also a ligand for the integrin LFA1, involves in leukocyte transmigration. As a cell adhesion molecule of the immunoglobulin superfamily, JAM-A protein involves in platelet adhesion, secretion and aggregation, and plays a crucial role in inflammatory thrombosis and atherosclerosis. In addition, it may be a potential therapeutic target for breast cancer.
  • Test
    Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
  • Latin name
    Mus musculus
  • Source
    Recombinants or rec. proteins
  • Group
    recombinants
  • Gene target
    JAM-A   F11R   Protein   tag   tag  
  • Gene symbol
    F11R, JAM2, JAM3, HLA-A, IGHV5-10-1, CIDEA, RPA1, CDC37P1, OR1Q1
  • Short name
    Recombinant Mouse JAM-A / F11R Protein (Fc tag)(Fc tag)
  • Technique
    Recombinant, Mouse, FC, mouses, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
  • Host
    mouse
  • Label
    Fc Tag
  • Species
    Mouse, Mouses
  • Alternative name
    Rec. Mouse JAM-A / F11 receptor Protein (fragment c detection labelled)(fragment c detection labelled)
  • Alternative technique
    rec, murine
  • Alternative to gene target
    F11 receptor, F11R and IDBG-104131 and ENSG00000158769 and 50848, protein binding, Cell surfaces, F11r and IDBG-204606 and ENSMUSG00000038235 and 16456, F11R and IDBG-630243 and ENSBTAG00000017846 and 281258
Gene info
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    junctional adhesion molecule 3
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    2001-04-26
  • Entrez gene record
  • RefSeq identity
  • Classification
    • Small nucleolar RNA protein coding host genes
    • Ig-like cell adhesion molecule family
    • V-set domain containing
  • VEGA ID
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    immunoglobulin heavy variable 5-10-1
  • Synonyms gene
  • Synonyms gene name
    • immunoglobulin heavy variable 5-A (provisional, gene/pseudogene)
    • immunoglobulin heavy variable 5-A (provisional)
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    2000-04-04
  • Entrez gene record
  • RefSeq identity
  • Classification
    • Immunoglobulin heavy locus at 14q32.33
  • VEGA ID
Gene info
Gene info
Gene info
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: The initial culturing of cells derived directly from fresh TISSUES.
  • Tree numbers
    • E01.370.225.500.223.500
    • E05.200.500.265.500
    • E05.242.223.500
    • E05.481.500.249.500
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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