Recombinant Mouse JAM-A / F11R Protein (Fc tag)(Fc tag)
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Catalog numberPKSM040670-50µg
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PricePlease ask
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Size50µg
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Synonym9130004G24;AA638916;ESTM33;JAM;JAM-1;JAM-A;Jcam;Jcam1;Ly106
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ActivityNA
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SequenceMet 1-Ala 242
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Fusion tagC-Fc
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AccessionNP_766235.1
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Expressed HostHEK293 Cells
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ShippingIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
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Purity> 94 % as determined by SDS-PAGE
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Endotoxin< 1.0 EU per μg of the protein as determined by the LAL method
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Stability and StorageSamples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Mol Mass50.2 kDa
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AP Mol Mass57 kDa
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FormulationLyophilized from sterile PBS, pH 7.4
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BackgroundJunctional adhesion molecule-A (JAM-A), also known as F11 receptor (F11R) or Cluster of Differentiation 321 (CD321), is a transmembrane protein expressed at tight junctions of epithelial and endothelial cells, as well as on circulating leukocytes. JAM-A protein serves as a serotype-independent receptor for mammalian orthoreoviruses (reoviruses). It is also a ligand for the integrin LFA1, involves in leukocyte transmigration. As a cell adhesion molecule of the immunoglobulin superfamily, JAM-A protein involves in platelet adhesion, secretion and aggregation, and plays a crucial role in inflammatory thrombosis and atherosclerosis. In addition, it may be a potential therapeutic target for breast cancer.
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TestMouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin nameMus musculus
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SourceRecombinants or rec. proteins
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Grouprecombinants
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Gene target
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Gene symbolF11R, JAM2, JAM3, HLA-A, IGHV5-10-1, CIDEA, RPA1, CDC37P1, OR1Q1
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Short nameRecombinant Mouse JAM-A / F11R Protein (Fc tag)(Fc tag)
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TechniqueRecombinant, Mouse, FC, mouses, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
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Hostmouse
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LabelFc Tag
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SpeciesMouse, Mouses
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Alternative nameRec. Mouse JAM-A / F11 receptor Protein (fragment c detection labelled)(fragment c detection labelled)
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Alternative techniquerec, murine
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Alternative to gene targetF11 receptor, F11R and IDBG-104131 and ENSG00000158769 and 50848, protein binding, Cell surfaces, F11r and IDBG-204606 and ENSMUSG00000038235 and 16456, F11R and IDBG-630243 and ENSBTAG00000017846 and 281258
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Gene info
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Identity
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Gene
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Long gene nameF11 receptor
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Synonyms gene
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Synonyms gene name
- junctional adhesion molecule 1
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Synonyms
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GenBank acession
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Locus
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Discovery year2001-04-10
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Ig-like cell adhesion molecule family
- V-set domain containing
- CD molecules
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namejunctional adhesion molecule 2
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Synonyms gene
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Synonyms
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GenBank acession
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Locus
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Discovery year2001-04-25
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Entrez gene record
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Pubmed identfication
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Classification
- CD molecules
- Ig-like cell adhesion molecule family
- I-set domain containing
- V-set domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namejunctional adhesion molecule 3
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Synonyms
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GenBank acession
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Locus
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Discovery year2001-04-26
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Entrez gene record
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RefSeq identity
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Classification
- Small nucleolar RNA protein coding host genes
- Ig-like cell adhesion molecule family
- V-set domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemajor histocompatibility complex, class I, A
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GenBank acession
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- C1-set domain containing
- Histocompatibility complex
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin heavy variable 5-10-1
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Synonyms gene
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Synonyms gene name
- immunoglobulin heavy variable 5-A (provisional, gene/pseudogene)
- immunoglobulin heavy variable 5-A (provisional)
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-04-04
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Entrez gene record
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RefSeq identity
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Classification
- Immunoglobulin heavy locus at 14q32.33
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecell death inducing DFFA like effector a
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Synonyms gene name
- cell death-inducing DFFA-like effector a
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-07-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namereplication protein A1
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Synonyms gene name
- replication protein A1 (70kD)
- replication protein A1, 70kDa
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Synonyms
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GenBank acession
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Locus
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Discovery year1993-12-14
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Nucleotide excision repair
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecell division cycle 37 pseudogene 1
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Synonyms gene name
- cell division cycle 37 homolog (S. cerevisiae) pseudogene 1
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Synonyms
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Locus
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Discovery year2009-01-29
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameolfactory receptor family 1 subfamily Q member 1
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Synonyms gene
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Synonyms gene name
- olfactory receptor, family 1, subfamily Q, member 1
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Synonyms
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Locus
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Discovery year1999-12-09
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Entrez gene record
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Classification
- Olfactory receptors, family 1
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VEGA ID
MeSH Data
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Name
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ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data