Recombinant Mouse IL-12 Receptor Subunit ß2/IL-12RB2 (C-Fc)

• Catalog number
  CK90-1000
• Price
  Please ask
• Size
  1 mg

• Description
  Recombinant Mouse IL-12 receptor beta 2 is produced by our Mammalian expression system and the target gene encoding Met1-Asn637 is expressed with a Fc tag at the C-terminus.
• Species reactivity
  Mouse
• Origin
  Human Cells
• Peptide sequence
  MAQTVRECSLALLFLFMWLLIKANIDVCKLGTVTVQPAPVIPLGSAANISCSLNPKQGCSHYPSSNELILLKFVNDVLVENLHGKKVHDHTGHSSTFQVTNLSLGMTLFVCKLNCSNSQKKPPVPVCGVEISVGVAPEPPQNISCVQEGENGTVACSWNSGKVTYLKTNYTLQLSGPNNLTCQKQCFSDNRQNCNRLDLGINLSPDLAESRFIVRVTAINDLGNSSSLPHTFTFLDIVIPLPPWDIRINFLNASGSRGTLQWEDEGQVVLNQLRYQPLNSTSWNMVNATNAKGKYDLRDLRPFTEYEFQISSKLHLSGGSWSNWSESLRTRTPEEEPVGILDIWYMKQDIDYDRQQISLFWKSLNPSEARGKILHYQVTLQEVTKKTTLQNTTRHTSWTRVIPRTGAWTASVSAANSKGASAPTHINIVDLCGTGLLAPHQVSAKSENMDNILVTWQPPKKADSAVREYIVEWRALQPGSITKFPPHWLRIPPDNMSALISENIKPYICYEIRVHALSESQGGCSSIRGDSKHKAPVSGPHITAITEKKERLFISWTHIPFPEQRGCILHYRIYWKERDSTAQPELCEIQYRRSQNSHPISSLQPRVTYVLWMTAVTAAGESPQGNEREFCPQGKANVDDIEGRMDEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK
• Estimated molecular weight
  98,4 kDa
• Protein purity
  Greater than 95% as determined by reducing SDS-PAGE.
• Endotoxin level
  Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
• Shipping condition
  Ambient/Room Temperature
• Package form
  Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.
• Storage conditions
  Lyophilized protein should be stored at below -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at below -20°C for 3 months.
• Reconstitution conditions
  Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 µg/ml.Dissolve the lyophilized protein in ddH2O.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
• UniProt number
  P97378
• Other related products
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus
• Additional description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  IL-12   Receptor   Subunit   ß2/IL-12RB2   C-Fc  
• Gene symbol
  IFNLR1, IL36G, IL25, IL22, IL18, IL37, IL6R, IL17C, IL17A, IL17D
• Short name
  Recombinant Mouse IL-12 Receptor Subunit ß2/IL-12RB2 (C-Fc)
• Technique
  Recombinant, Mouse, FC, mouses, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. novo advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Host
  mouse
• Species
  Mouses
• Alternative name
  Mouse IL-12 R beta2/IL-12RB2(C-Fc)
• Alternative technique
  rec, murine

Gene info

• Identity
  HGNC:18584
• Gene
  IFNLR1
• Long gene name
  interferon lambda receptor 1
• Synonyms gene
  • IL28RA
• Synonyms gene name
  • interleukin 28 receptor, alpha
  • interleukin 28 receptor, alpha (interferon, lambda receptor)
  • interferon, lambda receptor 1
• Synonyms
  • CRF2/12
  • IFNLR
  • IL-28R1
• GenBank acession
  • AY129153
• Locus
  1p36.11
• Discovery year
  2002-12-02
• Entrez gene record
  163702
• RefSeq identity
  • NM_170743
• Classification
  • Interferon receptors
• VEGA ID
  OTTHUMG00000003036

Gene info

• Identity
  HGNC:15741
• Gene
  IL36G
• Long gene name
  interleukin 36 gamma
• Synonyms gene
  • IL1F9
• Synonyms gene name
  • interleukin 1 family, member 9
• Synonyms
  • IL-1H1
  • IL-1RP2
  • IL-1F9
  • IL1H1
  • IL1E
• Synonyms name
  • interleukin-1 homolog 1
  • interleukin 1-related protein 2
  • interleukin-1 epsilon
• GenBank acession
  • AF200492
• Locus
  2q14.1
• Discovery year
  2002-08-02
• Entrez gene record
  56300
• Pubmed identfication
  • 10860666
  • 10744718
  • 11991722
  • 11991723
• RefSeq identity
  • NM_019618
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000131336

Gene info

• Identity
  HGNC:13765
• Gene
  IL25
• Long gene name
  interleukin 25
• Synonyms gene
  • IL17E
• Synonyms gene name
  • interleukin 17E
• Synonyms
  • IL-25
  • IL-17E
• GenBank acession
  • AF305200
• Locus
  14q11.2
• Discovery year
  2001-01-26
• Pubmed identfication
  • 11058597
  • 11754819
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000028749

Gene info

• Identity
  HGNC:14900
• Gene
  IL22
• Long gene name
  interleukin 22
• Synonyms
  • ILTIF
  • IL-21
  • zcyto18
  • IL-TIF
  • IL-D110
  • TIFa
  • TIFIL-23
  • IL-22
  • MGC79382
  • MGC79384
• Synonyms name
  • IL-10-related T-cell-derived inducible factor
• GenBank acession
  • AF279437
• Locus
  12q15
• Discovery year
  2001-03-12
• Entrez gene record
  50616
• Pubmed identfication
  • 10954742
  • 10875937
• RefSeq identity
  • NM_020525
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000169119
• Locus Specific Databases
  • LRG_1248

Gene info

• Identity
  HGNC:5986
• Gene
  IL18
• Long gene name
  interleukin 18
• Synonyms gene name
  • interleukin 18 (interferon-gamma-inducing factor)
• Synonyms
  • IGIF
  • IL1F4
  • IL-1g
  • IL-18
• Synonyms name
  • interferon-gamma-inducing factor
• GenBank acession
  • U90434
• Locus
  11q23.1
• Discovery year
  1997-07-25
• Entrez gene record
  3606
• Pubmed identfication
  • 7477296
  • 9693051
• RefSeq identity
  • NM_001562
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000167006

Gene info

• Identity
  HGNC:15563
• Gene
  IL37
• Long gene name
  interleukin 37
• Synonyms gene
  • IL1F7
• Synonyms gene name
  • interleukin 1 family, member 7 (zeta)
• Synonyms
  • FIL1
  • FIL1Z
  • FIL1(ZETA)
  • IL-1H4
  • IL-1RP1
  • IL-1F7
• Synonyms name
  • interleukin 1, zeta
  • interleukin-1 homolog 4
  • interleukin-1-related protein
• GenBank acession
  • AF201832
• Locus
  2q14.1
• Discovery year
  2002-08-02
• Entrez gene record
  27178
• Pubmed identfication
  • 10625660
  • 10512743
  • 12496389
• RefSeq identity
  • NM_014439
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000131345

Gene info

• Identity
  HGNC:6019
• Gene
  IL6R
• Long gene name
  interleukin 6 receptor
• Synonyms
  • CD126
  • IL-6R
  • IL-1Ra
  • IL6RA
  • gp80
• Synonyms name
  • membrane glycoprotein 80
  • interleukin 6 receptor subunit alpha
• GenBank acession
  • X12830
• Locus
  1q21.3
• Discovery year
  2001-06-22
• Entrez gene record
  3570
• Pubmed identfication
  • 8428753
  • 12633863
• RefSeq identity
  • NM_000565
• Classification
  • CD molecules
  • Interleukin receptors
  • Immunoglobulin like domain containing
• VEGA ID
  OTTHUMG00000036073

Gene info

• Identity
  HGNC:5983
• Gene
  IL17C
• Long gene name
  interleukin 17C
• Synonyms
  • IL-17C
  • CX2
  • IL-21
  • MGC126884
  • MGC138401
• GenBank acession
  • AF152099
• Locus
  16q24.2
• Discovery year
  2000-01-20
• Entrez gene record
  27189
• Pubmed identfication
  • 10639155
• RefSeq identity
  • NM_013278
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000173241

Gene info

• Identity
  HGNC:5981
• Gene
  IL17A
• Long gene name
  interleukin 17A
• Synonyms gene
  • CTLA8
  • IL17
• Synonyms gene name
  • interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)
• Synonyms
  • IL-17A
  • IL-17
• Synonyms name
  • cytotoxic T-lymphocyte-associated protein 8
• GenBank acession
  • U32659
• Locus
  6p12.2
• Discovery year
  1993-10-25
• Entrez gene record
  3605
• Pubmed identfication
  • 8390535
• RefSeq identity
  • NM_002190
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000014840
• Locus Specific Databases
  • LRG_1223

Gene info

• Identity
  HGNC:5984
• Gene
  IL17D
• Long gene name
  interleukin 17D
• Synonyms
  • IL-27
  • IL-17D
  • IL27
  • FLJ30846
• Synonyms name
  • interleukin 27
• GenBank acession
  • AY078238
• Locus
  13q12.11
• Discovery year
  2000-05-02
• Entrez gene record
  53342
• Pubmed identfication
  • 12097364
• RefSeq identity
  • NM_138284
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000016521

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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