Recombinant Mouse EGFR / HER1 / ErbB1 Protein (Fc tag) 100µg

  • Catalog number
    PKSM040366-100µg
  • Price
    Please ask
  • Size
    100µg
  • Activity
    Measured by its ability to bind human EGF in a functional ELISA.
  • Synonym
    9030024J15Rik;AI552599;Erbb;Errb1;Errp;wa-2;wa2;Wa5
  • Sequence
    Met 1-Ser 647
  • Fusion tag
    C-Fc
  • Accession
    Q01279
  • Expressed Host
    HEK293 Cells
  • Shipping
    In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
  • Purity
    > 90 % as determined by SDS-PAGE
  • Endotoxin
    < 1.0 EU per μg of the protein as determined by the LAL method
  • Stability and Storage
    Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Mol Mass
    96 kDa
  • AP Mol Mass
    130 kDa
  • Formulation
    Lyophilized from sterile PBS, pH 7.4
  • Background
    As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR protein plays a crucial role in signaling pathway in the regulation of cell proliferation, survival and differentiation. Binding of a ligand induces EGFR protein homo- or heterodimerization, the subsequent tyrosine autophosphorylation and initiates various down stream pathways (MAPK, PI3K/PKB and STAT). In addition, EGFR signaling also has been shown to exert action on carcinogenesis and disease progression, and thus EGFR protein is proposed as a target for cancer therapy currently.Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy
  • Test
    Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
  • Latin name
    Mus musculus
  • Source
    Recombinants or rec. proteins
  • Group
    recombinants
  • Gene target
    EGFR   HER1   ErbB1   Protein   tag   100µg  
  • Gene symbol
    EGFR-AS1, EGILA, EGFR, RHBDF1
  • Short name
    Recombinant Mouse EGFR / HER1 / ErbB1 Protein (Fc tag) 100µg
  • Technique
    Recombinant, Mouse, FC, mouses, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
  • Host
    mouse
  • Label
    Fc Tag
  • Species
    Mouse, Mouses
  • Alternative name
    Rec. Mouse epidermal growth factor receptor / HER1 / ErbB1 Protein (fragment c detection labelled) 100µg
  • Alternative technique
    rec, murine
  • Alternative to gene target
    epidermal growth factor receptor, ERBB and ERBB1 and HER1 and mENA and PIG61, EGFR and IDBG-16933 and ENSG00000146648 and 1956, transferase activity, nuclei, Egfr and IDBG-151194 and ENSMUSG00000020122 and 13649, EGFR and IDBG-644035 and ENSBTAG00000011628 and 407217
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    EGFR interacting lncRNA
  • Synonyms
  • Locus
  • Discovery year
    2019-09-27
  • Pubmed identfication
  • Classification
    • Long non-coding RNAs with non-systematic symbols
Gene info
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: The initial culturing of cells derived directly from fresh TISSUES.
  • Tree numbers
    • E01.370.225.500.223.500
    • E05.200.500.265.500
    • E05.242.223.500
    • E05.481.500.249.500
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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