Recombinant Mouse CD23 / FCER2 Protein (His tag)

  • Catalog number
    PKSM040540-50µg
  • Price
    Please ask
  • Size
    50µg
  • Synonym
    CD23;Fce2;Fcer2;Fcer2a;Ly-42
  • Activity
    NA
  • Sequence
    Glu 51-Pro 331
  • Fusion tag
    N-His
  • Accession
    P20693-1
  • Expressed Host
    HEK293 Cells
  • Shipping
    In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
  • Purity
    > 92 % as determined by SDS-PAGE
  • Endotoxin
    < 1.0 EU per μg of the protein as determined by the LAL method
  • Stability and Storage
    Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Mol Mass
    34.3 kDa
  • AP Mol Mass
    40-45 kDa
  • Formulation
    Lyophilized from sterile PBS, pH 7.4
  • Background
    Fc fragment of IgE, low affinity II, receptor for (CD23) or CD23 antigen is a member of the cluster of differentiation family. The cluster of differentiation (cluster of designation) (often abbreviated as CD) is a protocol used for the identification and investigation of cell surface molecules present on white blood cells initially but found in almost any kind of cell of the body, providing targets for immunophenotyping of cells. Physiologically, CD molecules can act in numerous ways, often acting as receptors or ligands (the molecule that activates a receptor) important to the cell. A signal cascade is usually initiated, altering the behavior of the cell (see cell signaling). Some CD proteins do not play a role in cell signaling, but have other functions, such as cell adhesion. CD23/FCER2 is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Increased levels of soluble CD23/FCER2 cause the recruitment of non-sensitised B-cells in the presentation of antigen peptides to allergen-specific B-cells, therefore increasing the production of allergen specific IgE. IgE, in turn, is known to upregulate the cellular expression of CD23 and Fc epsilon RI (high-affinity IgE receptor).
  • Conjugation
    histidine
  • Test
    Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
  • Latin name
    Mus musculus
  • Source
    Recombinants or rec. proteins
  • Group
    recombinants
  • Gene target
    CD23   FCER2   Protein   His   tag  
  • Gene symbol
    FCER2
  • Short name
    Recombinant Mouse CD23 / FCER2 Protein (His tag)
  • Technique
    Recombinant, Mouse, mouses, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
  • Host
    mouse
  • Label
    His
  • Species
    Mouse, Mouses
  • Alternative name
    Rec. Mouse CD23 / fragment c fragment on immunoglobuline E, low affinity II, receptor to measure (CD23) Protein (histidine detection labelled)
  • Alternative technique
    rec, murine
  • Alternative to gene target
    Fc fragment of IgE, low affinity II, receptor for (CD23), BLAST-2 and CD23 and CD23A and CLEC4J and FCE2 and IGEBF, FCER2 and IDBG-23316 and ENSG00000104921 and 2208, metal ion binding, Cell surfaces, Fcer2a and IDBG-130417 and ENSMUSG00000005540 and 14128, FCER2 and IDBG-643690 and ENSBTAG00000004270 and 407106
Gene info
  • Identity
  • Gene
  • Long gene name
    Fc fragment of IgE receptor II
  • Synonyms gene
  • Synonyms gene name
    • Fc fragment of IgE, low affinity II, receptor for (CD23A)
    • Fc fragment of IgE, low affinity II, receptor for (CD23)
  • Synonyms
  • Synonyms name
  • GenBank acession
  • Locus
  • Discovery year
    1988-08-05
  • Entrez gene record
  • RefSeq identity
  • Classification
    • C-type lectin domain containing
    • CD molecules
  • VEGA ID
MeSH Data
  • Name
  • Concept
    Scope note: The initial culturing of cells derived directly from fresh TISSUES.
  • Tree numbers
    • E01.370.225.500.223.500
    • E05.200.500.265.500
    • E05.242.223.500
    • E05.481.500.249.500
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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