Recombinant Mouse APOA1 Protein (Fc tag) 200µg

• Catalog number
  PKSM040440-200µg
• Price
  Please ask
• Size
  200µg

• Activity
  1. Measured by its binding ability in a functional ELISA.2. Immobilized mouse ApoAI at 10 μg/mL (100 μl/well) can bind  biotinylated human SCARB1, The EC50 of biotinylated human SCARB1 is 0.27 μg/mL.
• Synonym
  1-Sep;2-Sep;42248;42249;Alp-1;apo-AI;Apoa-1;apoA-I;Brp-14;Ltw-1;Lvtw-1
• Sequence
  Met 1-Gln 264
• Fusion tag
  C-Fc
• Accession
  Q00623
• Expressed Host
  HEK293 Cells
• Shipping
  In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
• Purity
  > 90 % as determined by SDS-PAGE
• Endotoxin
  < 1.0 EU per μg of the protein as determined by the LAL method
• Stability and Storage
  Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Mol Mass
  55.8 kDa
• AP Mol Mass
  60 kDa
• Formulation
  Lyophilized from sterile PBS, pH 7.4
• Background
  Apolipoprotein A1 (APOA1) is a member of the apolipoprotein family whose members are proteins bind with lipids and form lipoproteins to translate these oil-soluble lipids such as fat and cholesterol through lymphatic and circulatory system. APOA1 is the main component of high density lipoprotein (HDL) in plasma and is involved in the esterification of cholesterol as a cofactor of lecithin-cholesterol acyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters, and thus play a major role in cholesterol efflux from peripheral cells. As a major component of the HDL complex, APOA1 helps to clear cholesterol from arteries. APOA1 is also characterized as a prostacyclin stabilizing factor, and thus may have an anticlotting effect. Defects in encoding gene may result in HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. Men carrying a mutation may develop premature coronary artery disease.
• Technical data
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  APOA1   Protein   tag   200µg  
• Gene symbol
  APOA1, APOA1-AS
• Short name
  Recombinant Mouse APOA1 Protein (Fc tag) 200µg
• Technique
  Recombinant, Mouse, FC, mouses, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
• Host
  mouse
• Label
  Fc Tag
• Species
  Mouse, Mouses
• Alternative name
  Rec. Mouse apolipoprotein A-I Protein (fragment c detection labelled) 200µg
• Alternative technique
  rec, murine
• Alternative to gene target
  apolipoprotein A-I, APOA1 and IDBG-72644 and ENSG00000118137 and 335, lipoprotein particle binding, nuclei, Apoa1 and IDBG-161189 and ENSMUSG00000032083 and 11806, APOA1 and IDBG-630796 and ENSBTAG00000002258 and 281631

Gene info

• Identity
  HGNC:600
• Gene
  APOA1
• Long gene name
  apolipoprotein A1
• Synonyms gene name
  • apolipoprotein A-I
• GenBank acession
  • X02162
• Locus
  11q23.3
• Discovery year
  2001-06-22
• Entrez gene record
  335
• RefSeq identity
  • NM_000039
• Classification
  • Apolipoproteins
• VEGA ID
  OTTHUMG00000046112
• Locus Specific Databases
  • LRG_767

Gene info

• Identity
  HGNC:40079
• Gene
  APOA1-AS
• Long gene name
  APOA1 antisense RNA
• GenBank acession
  • DA327409
• Locus
  11q23.3
• Discovery year
  2014-01-04
• Entrez gene record
  104326055
• Pubmed identfication
  • 24388749
• RefSeq identity
  • NR_126362
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000150649

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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