Recombinant Mouse Activin Receptor IB/Activin RIB/ALK-4/ACVR1B (C-Fc)
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Catalog numberCM15-1000
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PricePlease ask
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Size1 mg
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DescriptionRecombinant Mouse Activin Receptor IB is produced by our Mammalian expression system and the target gene encoding Leu32-Glu126 is expressed with a Fc tag at the C-terminus.
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Species reactivityMouse
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OriginHuman Cells
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Peptide sequenceLLCACTSCLQTNYTCETDGACMVSIFNLDGVEHHVRTCIPKVELVPAGKPFYCLSSEDLRNTHCCYIDFCNKIDLRVPSGHLKEPAHPSMWGPVEVDDIEGRMDEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK
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Estimated molecular weight37,7 kDa
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Protein purityGreater than 95% as determined by reducing SDS-PAGE.
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Endotoxin levelLess than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
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Shipping conditionAmbient/Room Temperature
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Package formLyophilized from a 0.2 µm filtered solution of PBS,pH7.4.
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Storage conditionsLyophilized protein should be stored at below -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at below -20°C for 3 months.
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Reconstitution conditionsSee included datasheet or contact us for more information.
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UniProt numberQ61271
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TestMouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin nameMus musculus
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Additional descriptionThe receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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SourceRecombinants or rec. proteins
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Grouprecombinants
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Gene target
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Gene symbolACVR1B, ALK, ENPP7, MIR1302-4, PIRC18, PIRC16, SNORD114-4, MIR941-4
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Short nameRecombinant Mouse Activin Receptor IB/Activin RIB/ALK-4/ACVR1B (C-Fc)
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TechniqueRecombinant, Mouse, FC, mouses, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. novo advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Hostmouse
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SpeciesMouse, Mouses
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Alternative nameMouse Activin Receptor IB/Activin RIB/ALK-4/ACVR1B(C-Fc)
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Alternative techniquerec, murine
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Alternative to gene targetactivin A receptor, type IB, ACTRIB and ACVRLK4 and ALK4 and SKR2, ACVR1B and IDBG-33695 and ENSG00000135503 and 91, activin receptor activity, Cell surfaces, Acvr1b and IDBG-185560 and ENSMUSG00000000532 and 11479, ACVR1B and IDBG-632110 and ENSBTAG00000013555 and 539315
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Gene info
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Identity
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Gene
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Long gene nameactivin A receptor type 1B
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Synonyms gene
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Synonyms gene name
- activin A receptor, type IB
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Synonyms
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Locus
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Discovery year1994-12-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Type 1 receptor serine/threonine kinases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameALK receptor tyrosine kinase
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Synonyms gene name
- anaplastic lymphoma kinase (Ki-1)
- anaplastic lymphoma receptor tyrosine kinase
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Synonyms
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GenBank acession
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Locus
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Discovery year1993-08-24
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Receptor tyrosine kinases
- CD molecules
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameectonucleotide pyrophosphatase/phosphodiesterase 7
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2004-04-29
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Ectonucleotide pyrophosphatase/phosphodiesterase family
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemicroRNA 1302-4
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Synonyms gene
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Synonyms
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Locus
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Discovery year2008-11-03
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR1302 family
Gene info
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Identity
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Gene
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Long gene namepiwi-interacting RNA cluster 18
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Locus
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Discovery year2009-11-05
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Entrez gene record
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Pubmed identfication
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Classification
- Piwi-interacting RNA clusters
Gene info
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Identity
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Gene
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Long gene namepiwi-interacting RNA cluster 16
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Locus
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Discovery year2009-11-05
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Entrez gene record
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Pubmed identfication
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Classification
- Piwi-interacting RNA clusters
Gene info
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Identity
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Gene
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Long gene namesmall nucleolar RNA, C/D box 114-4
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Synonyms
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Locus
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Discovery year2006-09-26
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Small nucleolar RNAs, C/D box
Gene info
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Identity
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Gene
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Long gene namemicroRNA 941-4
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Synonyms gene
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Synonyms
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Locus
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Discovery year2007-10-24
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNAs
MeSH Data
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Name
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ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
