Recombinant Human TXNRD1 / TRXR1 Protein (aa 161-647, His tag) 100µg
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Catalog number
PKSH030732-100µg
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Price
Please ask
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Size
100µg
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Synonym
GRIM-12;TR;TR1;TRXR1;TXNR
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Activity
NA
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Sequence
Tyr 161-Cys 647
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Fusion tag
N-His
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Accession
Q16881-1
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Expressed Host
E. coli
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Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
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Purity
> 90 % as determined by SDS-PAGE
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Endotoxin
Please contact us for more information.
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Stability and Storage
Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Mol Mass
55 kDa
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AP Mol Mass
60 kDa
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Formulation
Lyophilized from sterile PBS, pH 7.4
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Reconstitution
Please refer to it for detailed information.
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Background
Thioredoxin reductase 1 (TXNRD1) which is a selenocysteine-containing protein is overexpressed in many malignancies. TXNRD1 plays a key role in regulating cell growth and transformation, and protects cells against oxidative damage. We investigated the association between TXNRD1 polymorphisms and ATDH susceptibility. Moreover, TXNRD1 is an essential selenium-containing enzyme involved in detoxification of reactive oxygen species (ROS) and redox signaling. And genetic variations in TXNRD1 favor the development of Drug-induced liver injury (DILI), which is the most common adverse drug reaction.
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Conjugation
histidine
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
TXNRD1, MIR647
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Short name
Recombinant TXNRD1 / TRXR1 Protein (aa 161-647, His tag) 100µg
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Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
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Label
His
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Species
Human, Humans
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Alternative name
Rec. H. sapiens TXNRD1 / TRXR1 Protein (aa 161-647, histidine detection labelled) 100µg
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Alternative technique
rec
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Gene info
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Identity
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Gene
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Long gene name
thioredoxin reductase 1
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Synonyms
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Synonyms name
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Locus
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Discovery year
1996-12-30
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Glutaredoxin domain containing
- Selenoproteins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
microRNA 647
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Synonyms gene
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Synonyms
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Locus
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Discovery year
2006-05-17
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Entrez gene record
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RefSeq identity
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Classification
MeSH Data
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Name
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Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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