Recombinant Human Tumor necrosis factor receptor superfamily member 12A (TNFRSF12A), partial

• Catalog number
  MBS1392721
• Price
  Please ask
• Size
  1 mg (E-Coli)

• Products_type
  Recombinant Protein
• Products_short_name
  [Tumor necrosis factor receptor superfamily member 12A (TNFRSF12A)]
• Other_names
  [tumor necrosis factor receptor superfamily member 12A; Tumor necrosis factor receptor superfamily member 12A; tumor necrosis factor receptor superfamily member 12A; TNF receptor superfamily member 12A; Fibroblast growth factor-inducible immediate-early response protein 14; FGF-inducible 14; Tweak-receptor; TweakR; CD_antigen: CD266]
• Products_gene_name
  [TNFRSF12A]
• Products_gene_name_syn
  [TNFRSF12A]
• Other_gene_names
  [TNFRSF12A; TNFRSF12A; FN14; CD266; TWEAKR; FN14; FGF-inducible 14; TweakR]
• Purity
  >85% (SDS-PAGE)
• Form
  Lyophilized or liquid (Format to be determined during the manufacturing process)
• Storage_stability
  Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
• Description
  Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Tumor   necrosis   factor   receptor   superfamily   member   12A   TNFRSF12A   partial  
• Gene symbol
  TNFRSF12A, IL12A
• Short name
  Recombinant Tumor necrosis factor receptor superfamily member 12A (TNFRSF12A), partial
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Host
  E Coli or Yeast or Baculovirus or Mammalian Cell
• Species
  Human, Humans
• Alternative name
  Rec. H. sapiens Tumor necrosis factor receptor supergroup member 12A (tumor necrosis factor receptor superfamily, member 12A), partial
• Alternative technique
  rec
• Alternative to gene target
  tumor necrosis factor receptor superfamily, member 12A, TNFRSF12A and IDBG-11328 and ENSG00000006327 and 51330, protein binding, Cell surfaces, Tnfrsf12a and IDBG-143687 and ENSMUSG00000023905 and 27279, BT.20111 and IDBG-635818 and ENSBTAG00000012082 and 617439
• Tissue
  tumor

Gene info

• Identity
  HGNC:18152
• Gene
  TNFRSF12A
• Long gene name
  TNF receptor superfamily member 12A
• Synonyms gene name
  • tumor necrosis factor receptor superfamily, member 12A
• Synonyms
  • FN14
  • TweakR
  • CD266
• GenBank acession
  • AB035480
• Locus
  16p13.3
• Discovery year
  2002-12-20
• Pubmed identfication
  • 10751351
  • 10551889
• Classification
  • Tumor necrosis factor receptor superfamily
  • CD molecules
• VEGA ID
  OTTHUMG00000129001

Gene info

• Identity
  HGNC:5969
• Gene
  IL12A
• Long gene name
  interleukin 12A
• Synonyms gene
  • NKSF1
• Synonyms gene name
  • interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
• Synonyms
  • CLMF
  • IL-12A
  • p35
  • NFSK
• Synonyms name
  • natural killer cell stimulatory factor 1, 35 kD subunit
  • cytotoxic lymphocyte maturation factor 1, p35
  • interleukin 12, p35
  • IL-12, subunit p35
  • NF cell stimulatory factor chain 1
  • interleukin-12 alpha chain
  • IL35 subunit
• GenBank acession
  • M65271
• Locus
  3q25.33
• Discovery year
  1991-08-08
• Entrez gene record
  3592
• Pubmed identfication
  • 1673147
• RefSeq identity
  • NM_000882
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000158942

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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