Recombinant Human Proprotein Convertase Subtilisin/Kexin Type 9/PCSK9 (C-AVI)
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Catalog numberCA84-500
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PricePlease ask
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Size500 ug
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DescriptionRecombinant Human Proprotein Convertase 9 is produced by our Mammalian expression system and the target gene encoding Gln31-Gln692 is expressed with a AVI tag at the C-terminus.
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Species reactivityHuman
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OriginHuman cells
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Peptide sequenceQEDEDGDYEELVLALRSEEDGLAEAPEHGTTATFHRCAKDPWRLPGTYVVVLKEETHLSQSERTARRLQAQAARRGYLTKILHVFHGLLPGFLVKMSGDLLELALKLPHVDYIEEDSSVFAQSIPWNLERITPPRYRADEYQPPDGGSLVEVYLLDTSIQSDHREIEGRVMVTDFENVPEEDGTRFHRQASKCDSHGTHLAGVVSGRDAGVAKGASMRSLRVLNCQGKGTVSGTLIGLEFIRKSQLVQPVGPLVVLLPLAGGYSRVLNAACQRLARAGVVLVTAAGNFRDDACLYSPASAPEVITVGATNAQDQPVTLGTLGTNFGRCVDLFAPGEDIIGASSDCSTCFVSQSGTSQAAAHVAGIAAMMLSAEPELTLAELRQRLIHFSAKDVINEAWFPEDQRVLTPNLVAALPPSTHGAGWQLFCRTVWSAHSGPTRMATAIARCAPDEELLSCSSFSRSGKRRGERMEAQGGKLVCRAHNAFGGEGVYAIARCCLLPQANCSVHTAPPAEASMGTRVHCHQQGHVLTGCSSHWEVEDLGTHKPPVLRPRGQPNQCVGHREASIHASCCHAPGLECKVKEHGIPAPQEQVTVACEEGWTLTGCSALPGTSHVLGAYAVDNTCVVRSRDVSTTGSTSEEAVTAVAICCRSRHLAQASQELQEFGGGLNDIFEAQKIEWHE
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Estimated molecular weight71,05 kDa
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Protein purityGreater than 95% as determined by reducing SDS-PAGE.
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Endotoxin levelLess than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
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Shipping conditionDry Ice/ice packs
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Package formSupplied as a 0.2 µm filtered solution of 50mM HEPES, 150mM NaCl, pH 7.4.
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Storage conditionsStore at below -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
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Reconstitution conditionsAlways centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 µg/ml.Dissolve the lyophilized protein in ddH2O.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
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UniProt numberQ8NBP7
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PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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SourceRecombinants or rec. proteins
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Grouprecombinants
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Gene target
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Gene symbolSMC4, PCSK9, PCK1, MYB, SFTPC, VCX3B, MAF, RFX1, EGR4
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Short nameRecombinant Proprotein Convertase Subtilisin/Kexin 9/PCSK9 (C-AVI)
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TechniqueRecombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. novo advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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SpeciesHuman, Humans
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Alternative nameHuman Proprotein Convertase 9/PCSK9(C-AVI)
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Alternative techniquerec
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Alternative to gene targetproprotein convertase subtilisin/kexin type 9, PCSK9 and IDBG-99082 and ENSG00000169174 and 255738, very-low-density lipoprotein particle receptor binding, Extracellular, Pcsk9 and IDBG-170186 and ENSMUSG00000044254 and 100102
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Gene info
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Identity
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Gene
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Long gene namestructural maintenance of chromosomes 4
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Synonyms gene
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Synonyms gene name
- SMC4 (structural maintenance of chromosomes 4, yeast)-like 1
- SMC4 structural maintenance of chromosomes 4-like 1 (yeast)
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Synonyms
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GenBank acession
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Locus
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Discovery year2001-02-22
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Entrez gene record
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Pubmed identfication
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Classification
- Structural maintenance of chromosomes proteins
- Condensin I subunits
- Condensin II subunits
- MicroRNA protein coding host genes
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameproprotein convertase subtilisin/kexin type 9
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Synonyms gene
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Synonyms gene name
- hypercholesterolemia, autosomal dominant 3
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Synonyms
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GenBank acession
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Locus
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Discovery year2003-05-13
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Proprotein convertase subtilisin/kexin family
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namephosphoenolpyruvate carboxykinase 1
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Synonyms gene name
- phosphoenolpyruvate carboxykinase 1 (soluble)
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Synonyms
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Locus
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Discovery year1990-09-10
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Entrez gene record
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Pubmed identfication
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameMYB proto-oncogene, transcription factor
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Synonyms gene name
- v-myb avian myeloblastosis viral oncogene homolog
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Synonyms
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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Classification
- Myb/SANT domain containing
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namesurfactant protein C
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Synonyms gene
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Synonyms gene name
- surfactant, pulmonary-associated protein C
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Synonyms
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Synonyms name
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Locus
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Discovery year1988-05-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- BRICHOS domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namevariable charge X-linked 3B
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Synonyms
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Locus
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Discovery year2005-01-11
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Classification
- Variable charge X/Y family
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameMAF bZIP transcription factor
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Synonyms gene name
- v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
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Synonyms
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Locus
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Discovery year1991-08-01
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Entrez gene record
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Pubmed identfication
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Classification
- Basic leucine zipper proteins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameregulatory factor X1
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Synonyms gene name
- regulatory factor X, 1 (influences HLA class II expression)
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Synonyms
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Synonyms name
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Locus
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Discovery year1991-11-06
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Regulatory factor X family
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameearly growth response 4
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Synonyms
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Locus
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Discovery year1992-07-27
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Zinc fingers C2H2-type
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VEGA ID
MeSH Data
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Name
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ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data