Recombinant Human Pro-Neuregulin-1/NRG1-ß 1/HRG1-ß 1 (Ser2-Lys246)

• Catalog number
  C753-10
• Price
  Please ask
• Size
  10 ug

• Description
  Recombinant Human Neuregulin-1 beta is produced by our E.coli expression system and the target gene encoding Ser2-Lys246 is expressed.
• Species reactivity
  Human
• Origin
  Escherichia coli
• Peptide sequence
  MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPQLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYKHLGIEFMEAEELYQK
• Estimated molecular weight
  26,9 kDa
• Protein purity
  Greater than 95% as determined by reducing SDS-PAGE.
• Endotoxin level
  Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
• Shipping condition
  Ambient/Room Temperature
• Package form
  Lyophilized from a 0.2 µm filtered solution of 4mM HCl.
• Storage conditions
  Lyophilized protein should be stored at below -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at below -20°C for 3 months.
• Reconstitution conditions
  Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 µg/ml.Dissolve the lyophilized protein in ddH2O.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
• UniProt number
  Q02297-6
• Other related products
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Pro-Neuregulin-1/NRG1-ß   1/HRG1-ß   Ser2-Lys246  
• Gene symbol
  NRG1-IT1, NRG1, NRG1-IT3, SLC48A1
• Short name
  Recombinant Pro-Neuregulin-1/NRG1-ß 1/HRG1-ß 1 (Ser2-Lys246)
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. novo advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Humans
• Alternative name
  Human NRG1-beta 1/HRG1-beta 1(Ser2-Lys246)
• Alternative technique
  rec
• Alternative to gene target
  neuregulin 1, ARIA and GGF and GGF2 and HGL and HRG and HRG1 and HRGA and MST131 and MSTP131 and NDF and NRG1-IT2 and SMDF, NRG1 and IDBG-16182 and ENSG00000157168 and 3084, ErbB-3 class receptor binding, nuclei, Nrg1 and IDBG-146861 and ENSMUSG00000062991 and 211323, NRG1 and IDBG-628923 and ENSBTAG00000004150 and 281361

Gene info

• Identity
  HGNC:43633
• Gene
  NRG1-IT1
• Long gene name
  NRG1 intronic transcript 1
• Synonyms gene name
  • NRG1 intronic transcript 1 (non-protein coding)
• GenBank acession
  • BC037250
• Locus
  8p12
• Discovery year
  2011-12-06
• Classification
  • Intronic transcripts
• VEGA ID
  OTTHUMG00000163966

Gene info

• Identity
  HGNC:7997
• Gene
  NRG1
• Long gene name
  neuregulin 1
• Synonyms gene
  • HGL
  • NRG1-IT2
• Synonyms gene name
  • NRG1 intronic transcript 2 (non-protein coding)
• Synonyms
  • HRG
  • NDF
  • GGF
• GenBank acession
  • L12261
• Locus
  8p12
• Discovery year
  1999-03-19
• Entrez gene record
  3084
• Pubmed identfication
  • 1350381
  • 8095334
• Classification
  • I-set domain containing
  • Neuregulins
• VEGA ID
  OTTHUMG00000163918

Gene info

• Identity
  HGNC:43635
• Gene
  NRG1-IT3
• Long gene name
  NRG1 intronic transcript 3
• Synonyms gene name
  • NRG1 intronic transcript 3 (non-protein coding)
• Locus
  8p12
• Discovery year
  2011-12-06
• Classification
  • Intronic transcripts
• VEGA ID
  OTTHUMG00000164003

Gene info

• Identity
  HGNC:26035
• Gene
  SLC48A1
• Long gene name
  solute carrier family 48 member 1
• Synonyms gene name
  • solute carrier family 48 (heme transporter), member 1
• Synonyms
  • FLJ20489
  • hHRG-1
  • HRG1
• Locus
  12q13.11
• Discovery year
  2008-10-17
• Entrez gene record
  55652
• Pubmed identfication
  • 18418376
• RefSeq identity
  • NM_017842
• Classification
  • Solute carriers
• VEGA ID
  OTTHUMG00000156983

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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