Recombinant Human Perforin-1(PRF1)

• Catalog number
  RPC20065
• Price
  Please ask
• Size
  100 μg

• Verified reactivity
  Homo sapiens (Human)
• Protein number
  P14222
• Gene number
  PRF1
• Other name
  Cytolysin; Lymphocyte pore-forming protein ; PFP
• Protein origin
  E.coli
• Protein region
  22-555aa
• Protein sequence
  PCHTAARSECKRSHKFVPGAWLAGEGVDVTSLRRSGSFPVDTQRFLRPDGTCTLCENALQEGTLQRLPLALTNWRAQGSGCQRHVTRAKVSSTEAVARDAARSIRNDWKVGLDVTPKPTSNVHVSVAGSHSQAANFAAQKTHQDQYSFSTDTVECRFYSFHVVHTPPLHPDFKRALGDLPHHFNASTQPAYLRLISNYGTHFIRAVELGGRISALTALRTCELALEGLTDNEVEDCLTVEAQVNIGIHGSISAEAKACEEKKKKHKMTASFHQTYRERHSEVVGGHHTSINDLLFGIQAGPEQYSAWVNSLPGSPGLVDYTLEPLHVLLDSQDPRREALRRALSQYLTDRARWRDCSRPCPPGRQKSPRDPCQCVCHGSAVTTQDCCPRQRGLAQLEVTFIQAWGLWGDWFTATDAYVKLFFGGQELRTSTVWDNNNPIWSVRLDFGDVLLATGGPLRLQVWDQDSGRDDDLLGTCDQAPKSGSHEVRCNLNHGHLKFRYHARCLPHLGGGTCLDYVPQMLLGEPPGNRSGAVW
• Information about sequence
  Full Length
• Expected molecular weight
  75.1kDa
• Protein purity
  ≥ 90%
• Storage recommendation
  Aliquot and store at -20°C. Minimize freezing and thawing.
• Use before
  1 year
• Shipping requirements
  Blue ice
• Estimated production time
  7-11 business days
• Notes
  For research use only. Not for diagnostic procedures.
• Hyperlink
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Perforin-1   PRF1  
• Gene symbol
  PRF1
• Short name
  Recombinant Perforin-1(PRF1)
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. bioma advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Label
  N-terminal 6xHis-SUMO-tagged
• Species
  Human, Humans
• Alternative name
  Rec. H. sapiens Perforin-1(perforin 1 (pore forming protein))
• Alternative technique
  rec
• Alternative to gene target
  perforin 1 (pore forming protein), FLH2 and HPLH2 and P1 and PFN1 and PFP, PRF1 and IDBG-77451 and ENSG00000180644 and 5551, wide pore channel activity, Extracellular, Prf1 and IDBG-155739 and ENSMUSG00000037202 and 18646, BT.21975 and IDBG-629772 and ENSBTAG00000001008 and 369025

Gene info

• Identity
  HGNC:9360
• Gene
  PRF1
• Long gene name
  perforin 1
• Synonyms gene name
  • perforin 1 (pore forming protein)
• Synonyms
  • PFP
  • P1
  • HPLH2
• Synonyms name
  • Perforin
  • perforin 1 (preforming protein)
• GenBank acession
  • BC047695
• Locus
  10q22.1
• Discovery year
  1989-02-23
• Entrez gene record
  5551
• Pubmed identfication
  • 1505959
  • 2592021
• RefSeq identity
  • NM_005041
• Classification
  • C2 domain containing
• VEGA ID
  OTTHUMG00000018412
• Locus Specific Databases
  • PRF1base: Mutation registry for Familiar haemophagocytic lymphohistiocytosis, type II (FHL2)
  • LRG_94

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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