Recombinant Human PARP Enzyme (HSA)

Keep at

-20° C
Reagent list
Assay performance

CometAssay, DNA Damage, PCR and Molecular Biology, Oxidative Damage, PARP research.
More advice

Trevigen offers Angiogenesis/Cell Differentiation, antibodies, apoptosis, signal_transduction, Basement Membrane Proteins.
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Description

Enzymes are cleaving the substrate. If the substrate is DNA they are called restriction enzymes. Activating enzymes will cut off the domain that is biological active to become functional.
Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Source

Recombinants or rec. proteins
Group

recombinants

Gene target

PARP HSA
Gene symbol

TNKS2, TIPARP, PARP1, PARP12, TNKS, MIR3591, MIR3150A, MIR146A, MIR374A, MIR18A
Short name

Recombinant PARP Enzyme (HSA)
Technique

Recombinant, Enzyme, enzymes, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Trevigen advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
Species

Human, Humans
Alternative name

Rec. H. sapiens PARP Enzyme (HSA)
Alternative technique

rec, enzymes

Identity

HGNC:15677
Gene

TNKS2
Long gene name

tankyrase 2
Synonyms gene name
- tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
Synonyms
- TNKL
- TANK2
- PARP-5b
- PARP-5c
- PARP5B
- PARP5C
- pART6
- ARTD6
Synonyms name
- TRF1-interacting ankyrin-related ADP-ribose polymerase 2
GenBank acession
- AF342982
Locus

10q23.32
Discovery year

2001-05-10
Entrez gene record

80351
RefSeq identity
- NM_025235
Classification
- Poly(ADP-ribose) polymerases
- Sterile alpha motif domain containing
- Ankyrin repeat domain containing
VEGA ID

OTTHUMG00000018747

Identity

HGNC:270
Gene

PARP1
Long gene name

poly(ADP-ribose) polymerase 1
Synonyms gene
- PPOL
- ADPRT
Synonyms gene name
- ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)
- poly (ADP-ribose) polymerase family, member 1
Synonyms
- PARP
- ARTD1
GenBank acession
- BC037545
Locus

1q42.12
Discovery year

1986-01-01
Entrez gene record

142
Pubmed identfication
- 10964595
RefSeq identity
- NM_001618
Classification
- Zinc fingers PARP-type
- Zinc fingers
- Poly(ADP-ribose) polymerases
VEGA ID

OTTHUMG00000037556

Identity

HGNC:11941
Gene

TNKS
Long gene name

tankyrase
Synonyms gene name
- tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
Synonyms
- TIN1
- TINF1
- TNKS1
- PARP-5a
- PARP5A
- pART5
- ARTD5
Synonyms name
- TRF1-interacting ankyrin-related ADP-ribose polymerase 1
GenBank acession
- AF082556
Locus

8p23.1
Discovery year

1999-01-08
Entrez gene record

8658
Pubmed identfication
- 9822378
- 10198177
RefSeq identity
- NM_003747
Classification
- Poly(ADP-ribose) polymerases
- Sterile alpha motif domain containing
- Ankyrin repeat domain containing
- MicroRNA protein coding host genes
VEGA ID

OTTHUMG00000090481

Name

Primary Cell Culture
Concept

Scope note: The initial culturing of cells derived directly from fresh TISSUES.
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data