Recombinant Human Osteomodulin / OMD Protein (His Tag) 200µg

• Catalog number
  PKSH031406-200µg
• Price
  Please ask
• Size
  200µg

• Synonym
  OSAD;SLRR2C
• Activity
  NA
• Sequence
  Met1-Glu421
• Fusion tag
  C-His
• Accession
  NP_005005.1
• Expressed Host
  HEK293 Cells
• Shipping
  In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
• Purity
  ＞95 % as determined by SDS-PAGE.
• Endotoxin
  ＜1.0 EU per µg as determined by the LAL method.
• Stability and Storage
  Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Mol Mass
  48.6 kDa
• AP Mol Mass
  48.6 kDa
• Formulation
  Lyophilized from sterile PBS, pH 7.4
• Reconstitution
  Please refer to it for detailed information.
• Background
  Osteomodulin (OMD), also known as Osteoadherin (OSAD), Keratan sulfate proteoglycan osteomodulin, KSPG osteomodulin, and SLRR2C, is a secreted protein which belongs to the small leucine-rich proteoglycan (SLRP) family and Class II subfamily. SLRP family proteins are normally found in extracellular matrices, but Osteomodulin is the only member restricted to mineralized tissues. Osteomodulin is primarily expressed by osteoblasts and might have a role in regulation of mineralization. In bone OSAD has been localized in primary spongiosa within the bovine fetal rib growth plate. Moreover, in situ hybridization has shown expression of OSAD in osteoblasts close to the cartilage and bone border in the growth plate of rat femur. OSAD may play an important role during tooth development and biomineralization of dentin. Osteomodulin is a cell binding keratan sulfate proteoglycan which was recently isolated from mineralized bovine bone and subsequently cloned and sequenced. Osteomodulin may be implicated in biomineralization processes. It has a function in binding of osteoblasts via the alpha (V) beta (3)-integrin. It is likely that Osteomodulin is an osteoblast maturation marker that is induced by osteoclast activity. Osteomodulin is also an early marker for terminally differentiated matrix producing osteoblasts.
• Product URL
• PDF URL
• Conjugation
  histidine
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Osteomodulin   OMD   Protein   His   Tag   200µg  
• Gene symbol
  OMD
• Short name
  Recombinant Osteomodulin / OMD Protein (His Tag) 200µg
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
• Label
  His
• Species
  Human, Humans
• Alternative name
  Rec. H. sapiens Osteomodulin / osteomodulin Protein (histidine detection labelled) 200µg
• Alternative technique
  rec
• Alternative to gene target
  osteomodulin, OSAD and SLRR2C, OMD and IDBG-76206 and ENSG00000127083 and 4958, protein binding, Extracellular, Omd and IDBG-151149 and ENSMUSG00000048368 and 27047, OMD and IDBG-636793 and ENSBTAG00000011836 and 280885

Gene info

• Identity
  HGNC:8134
• Gene
  OMD
• Long gene name
  osteomodulin
• Synonyms
  • osteoadherin
  • SLRR2C
• Synonyms name
  • osteoadherin proteoglycan
• GenBank acession
  • AB000114
• Locus
  9q22.31
• Discovery year
  1997-11-11
• Entrez gene record
  4958
• RefSeq identity
  • NM_005014
• Classification
  • Small leucine rich repeat proteoglycans
• VEGA ID
  OTTHUMG00000020225

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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