Recombinant Human Oncostatin M/OSM (N-6His)

• Catalog number
  C099-500
• Price
  Please ask
• Size
  500 ug

• Description
  Recombinant Human Oncostatin M is produced by our E.coli expression system and the target gene encoding Ala26-Arg221 is expressed with a 6His tag at the N-terminus.
• Species reactivity
  Human
• Origin
  Escherichia coli
• Peptide sequence
  MGSSHHHHHHSSGLVPRGSHMAAIGSCSKEYRVLLGQLQKQTDLMQDTSRLLDPYIRIQGLDVPKLREHCRERPGAFPSEETLRGLGRRGFLQTLNATLGCVLHRLADLEQRLPKAQDLERSGLNIEDLEKLQMARPNILGLRNNIYCMAQLLDNSDTAEPTKAGRGASQPPTPTPASDAFQRKLEGCRFLHGYHRFMHSVGRVFSKWGESPNRSRR
• Estimated molecular weight
  24,44 kDa
• Protein purity
  Greater than 95% as determined by reducing SDS-PAGE.
• Endotoxin level
  Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
• Shipping condition
  Ambient/Room Temperature
• Package form
  Lyophilized from a 0.2 µm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
• Storage conditions
  Lyophilized protein should be stored at below -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at below -20°C for 3 months.
• Reconstitution conditions
  Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 µg/ml.Dissolve the lyophilized protein in ddH2O.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
• UniProt number
  P13725
• Other related products
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Oncostatin   M/OSM   N-6His  
• Gene symbol
  OSM, CCM2, IFT172, KIF17
• Short name
  Recombinant Oncostatin M/OSM (N-6His)
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. novo advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  Human Oncostatin M/OSM(N-6His)
• Alternative technique
  rec
• Alternative to gene target
  oncostatin M, OSM and IDBG-4002 and ENSG00000099985 and 5008, growth factor activity, Extracellular, Osm and IDBG-142284 and ENSMUSG00000058755 and 18413, BT.45038 and IDBG-636338 and ENSBTAG00000016163 and 319086

Gene info

• Identity
  HGNC:8506
• Gene
  OSM
• Long gene name
  oncostatin M
• Synonyms
  • MGC20461
• GenBank acession
  • AF129855
• Locus
  22q12.2
• Discovery year
  1992-07-09
• Entrez gene record
  5008
• Pubmed identfication
  • 1717982
• RefSeq identity
  • NM_020530
• Classification
  • Interleukin 6 type cytokine family
• VEGA ID
  OTTHUMG00000150913

Gene info

• Identity
  HGNC:21708
• Gene
  CCM2
• Long gene name
  CCM2 scaffold protein
• Synonyms gene
  • C7orf22
• Synonyms gene name
  • chromosome 7 open reading frame 22
  • cerebral cavernous malformation 2
  • CCM2 scaffolding protein
• Synonyms
  • MGC4607
  • OSM
• Synonyms name
  • malcavernin
  • osmosensing scaffold for MEKK3
• GenBank acession
  • BC004903
• Locus
  7p13
• Discovery year
  2003-07-14
• Entrez gene record
  83605
• Pubmed identfication
  • 9811928
• RefSeq identity
  • NM_031443
• Classification
  • CCM adhesion complex
• VEGA ID
  OTTHUMG00000129246
• Locus Specific Databases
  • LRG_664

Gene info

• Identity
  HGNC:30391
• Gene
  IFT172
• Long gene name
  intraflagellar transport 172
• Synonyms gene name
  • intraflagellar transport 172 homolog (Chlamydomonas)
• Synonyms
  • SLB
  • wim
  • osm-1
  • NPHP17
  • BBS20
• Synonyms name
  • wimple homolog
• GenBank acession
  • AB033005
• Locus
  2p23.3
• Discovery year
  2005-11-02
• Entrez gene record
  26160
• Pubmed identfication
  • 10788441
  • 10574461
  • 24140113
  • 26763875
• RefSeq identity
  • NM_015662
• Classification
  • WD repeat domain containing
  • IFT-B2 complex
• VEGA ID
  OTTHUMG00000128425

Gene info

• Identity
  HGNC:19167
• Gene
  KIF17
• Long gene name
  kinesin family member 17
• Synonyms
  • KIAA1405
  • KIF3X
  • KIF17B
  • OSM-3
  • KLP-2
• Synonyms name
  • kinesin-like protein KIF17
  • KIF3-related motor protein
  • KIF17 variant protein
• GenBank acession
  • AB037826
• Locus
  1p36.12
• Discovery year
  2002-08-29
• Entrez gene record
  57576
• Pubmed identfication
  • 10846156
• RefSeq identity
  • NM_020816
• Classification
  • Kinesins
• VEGA ID
  OTTHUMG00000002863

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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