Recombinant Human N-Acetylglucosamine-6-Sulfatase/GNS (C-6His)

• Catalog number
  C354-500
• Price
  Please ask
• Size
  500 ug

• Description
  Recombinant Human N-Acetylglucosamine-6-Sulfatase is produced by our Mammalian expression system and the target gene encoding Val37-Leu552 is expressed with a 6His tag at the C-terminus.
• Species reactivity
  Human
• Origin
  Human cells
• Peptide sequence
  VFGVAAGTRRPNVVLLLTDDQDEVLGGMTPLKKTKALIGEMGMTFSSAYVPSALCCPSRASILTGKYPHNHHVVNNTLEGNCSSKSWQKIQEPNTFPAILRSMCGYQTFFAGKYLNEYGAPDAGGLEHVPLGWSYWYALEKNSKYYNYTLSINGKARKHGENYSVDYLTDVLANVSLDFLDYKSNFEPFFMMIATPAPHSPWTAAPQYQKAFQNVFAPRNKNFNIHGTNKHWLIRQAKTPMTNSSIQFLDNAFRKRWQTLLSVDDLVEKLVKRLEFTGELNNTYIFYTSDNGYHTGQFSLPIDKRQLYEFDIKVPLLVRGPGIKPNQTSKMLVANIDLGPTILDIAGYDLNKTQMDGMSLLPILRGASNLTWRSDVLVEYQGEGRNVTDPTCPSLSPGVSQCFPDCVCEDAYNNTYACVRTMSALWNLQYCEFDDQEVFVEVYNLTADPDQITNIAKTIDPELLGKMNYRLMMLQSCSGPTCRTPGVFDPGYRFDPRLMFSNRGSVRTRRFSKHLLVDHHHHHH
• Estimated molecular weight
  59,35 kDa
• Protein purity
  Greater than 95% as determined by reducing SDS-PAGE.
• Endotoxin level
  Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
• Shipping condition
  Dry Ice/ice packs
• Package form
  Supplied as a 0.2 µm filtered solution of 20mM TrisHCl, 150mM NaCl,10% Glycerol,pH 8.0.
• Storage conditions
  Store at below -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
• Reconstitution conditions
  See included datasheet or contact us for more information.
• UniProt number
  P15586
• Other related products
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  N-Acetylglucosamine-6-Sulfatase/GNS   C-6His  
• Gene symbol
  GNS, MIR1302-6, PIRC28, PIRC24, PIRC26, PIRC27, PIRC25, ADCP1
• Short name
  Recombinant N-Acetylglucosamine-6-Sulfatase/GNS (C-6His)
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. novo advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  Recombinant Human GNS(C-6His)
• Alternative technique
  rec

Gene info

• Identity
  HGNC:4422
• Gene
  GNS
• Long gene name
  glucosamine (N-acetyl)-6-sulfatase
• Synonyms name
  • Sanfilippo disease IIID
  • N-acetylglucosamine-6-sulfatase
• Locus
  12q14.3
• Discovery year
  1988-06-09
• Entrez gene record
  2799
• Classification
  • Sulfatases
• VEGA ID
  OTTHUMG00000168819

Gene info

• Identity
  HGNC:35298
• Gene
  MIR1302-6
• Long gene name
  microRNA 1302-6
• Synonyms gene
  • MIRN1302-6
• Synonyms
  • hsa-mir-1302-6
• Locus
  7p21.1
• Discovery year
  2008-11-03
• Entrez gene record
  100302140
• RefSeq identity
  • NR_031635
• Classification
  • MicroRNA MIR1302 family

Gene info

• Identity
  HGNC:37532
• Gene
  PIRC28
• Long gene name
  piwi-interacting RNA cluster 28
• Locus
  6
• Discovery year
  2009-11-05
• Entrez gene record
  100313893
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37528
• Gene
  PIRC24
• Long gene name
  piwi-interacting RNA cluster 24
• Locus
  6
• Discovery year
  2009-11-05
• Entrez gene record
  100313810
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37530
• Gene
  PIRC26
• Long gene name
  piwi-interacting RNA cluster 26
• Locus
  6
• Discovery year
  2009-11-05
• Entrez gene record
  100313852
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37531
• Gene
  PIRC27
• Long gene name
  piwi-interacting RNA cluster 27
• Locus
  6
• Discovery year
  2009-11-05
• Entrez gene record
  100313907
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37529
• Gene
  PIRC25
• Long gene name
  piwi-interacting RNA cluster 25
• Locus
  6
• Discovery year
  2009-11-05
• Entrez gene record
  100313851
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:229
• Gene
  ADCP1
• Long gene name
  adenosine deaminase complexing protein 1
• Locus
  6
• Discovery year
  1986-01-01
• Entrez gene record
  106
• Pubmed identfication
  • 279003
  • 6933468
  • 6974523

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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