Thyroid Peroxidase, Recombinant, Human (TPO, TMA, Thyroid Microsomal Antigen)

• Catalog number
  MBS638319
• Price
  Please ask
• Size
  5x0.02 mg

• Products_type
  Recombinant Protein
• Products_short_name
  [Thyroid Peroxidase]
• Other_names
  [thyroid peroxidase isoform a; Thyroid peroxidase; thyroid peroxidase; thyroperoxidase; thyroid microsomal antigen; thyroid peroxidase]
• Other_gene_names
  [TPO; TPO; MSA; TPX; TDH2A; TPO]
• Purity
  Highly Purified95% (SDS-PAGE)
• Form
  Supplied as a liquid in 16mM HEPES, pH 7.6, 160mM sodium chloride, 0.08mM potassium iodide 20% glycerol.
• Storage_stability
  May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 6 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
• Description
  Antigens are peptides or recombinant or native dependent on the production method.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Conjugate
  Peroxidases with EC number 1.11.1.x are catalyzing the reaction of ROOR' + electron donor (2 e−) + 2H+ → ROH + R'OH
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Thyroid   TPO   TMA   Thyroid   Microsomal  
• Gene symbol
  TPO, THPO
• Short name
  Thyroid , Recombinant, (TPO, TMA, Thyroid Microsomal Antigen)
• Technique
  Recombinant, antigen, antigenes, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Host
  Sf9 insect cells
• Label
  peroxidase
• Species
  Human, Humans
• Alternative name
  Thyroid Peroxidase, Rec., H. sapiens (TPO, TMA, Thyroid Microsomal protein)
• Alternative technique
  rec, antigenes
• Tissue
  thyroid

Gene info

• Identity
  HGNC:12015
• Gene
  TPO
• Long gene name
  thyroid peroxidase
• Synonyms
  • TPX
• Locus
  2p25.3
• Discovery year
  1986-01-01
• Entrez gene record
  7173
• RefSeq identity
  • NM_000547
• Classification
  • Sushi domain containing
• VEGA ID
  OTTHUMG00000090271

Gene info

• Identity
  HGNC:11795
• Gene
  THPO
• Long gene name
  thrombopoietin
• Synonyms gene
  • MGDF
• Synonyms
  • TPO
  • MPLLG
• Synonyms name
  • prepro-thrombopoietin
  • megakaryocyte stimulating factor
  • myeloproliferative leukemia virus oncogene ligand
  • megakaryocyte growth and development factor
  • MPL ligand
  • megakaryocyte colony-stimulating factor
  • c-mpl ligand
  • thrombopoietin nirs variant 1
• Locus
  3q27.1
• Discovery year
  1994-11-04
• Entrez gene record
  7066
• Pubmed identfication
  • 8202154
• RefSeq identity
  • NM_000460
• Classification
  • Receptor ligands
• VEGA ID
  OTTHUMG00000156745
• Locus Specific Databases
  • LRG_580

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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