Recombinant Human LILRB3 / LIR3 / ILT5 / CD85a Protein (His tag) 100µg
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Catalog number
PKSH030947-100µg
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Price
Please ask
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Size
100µg
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Synonym
CD85A;HL9;ILT-5;ILT5;LILRA6;LIR-3;LIR3;MGC138403;PIRB;XXbac-BCX105G6.7
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Activity
NA
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Sequence
Met 1-Glu 443
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Fusion tag
C-His
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Accession
NP_006855.2
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Expressed Host
HEK293 Cells
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Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
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Purity
＞97 % as determined by SDS-PAGE
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Endotoxin
＜1.0 EU per µg as determined by the LAL method
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Stability and Storage
Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Mol Mass
47.6 kDa
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AP Mol Mass
55-60 kDa
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Formulation
Lyophilized from sterile PBS, pH 7.4
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Reconstitution
Please refer to it for detailed information.
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Background
Leukocyte immunoglobulin-like receptor subfamily B member 3, also known as Leukocyte immunoglobulin-like receptor 3, Immunoglobulin-like transcript 5, Monocyte inhibitory receptor HL9, CD85 antigen-like family member A, CD85a and LILRB3, is a single-pass type I membrane protein which belongs to the leukocyte receptor cluster (LRC) present on 19q13.4. LILRB3 / CD85a contains four Ig-like C2-type (immunoglobulin-like) domains. LILRB3 / CD85a contains three copies of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases. LILRB3 / CD85a is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found.
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Conjugation
histidine
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
LILRB3
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Short name
Recombinant LILRB3 / LIR3 / ILT5 / CD85a Protein (His tag) 100µg
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Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
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Label
His
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Species
Human, Humans
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Alternative name
Rec. H. sapiens leukocyte immunoglobulin-like receptor, subfamily B (including TM and ITIM domains), member 3 / LIR3 / ILT5 / CD85a Protein (histidine detection labelled) 100µg
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Alternative technique
rec
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Alternative to gene target
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3, LILRB3 and IDBG-68373 and ENSG00000204577 and 102724997,102725015,102725027,102725029,102725031,102725034,102725035,102725273,11025, protein binding, Plasma membranes
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Gene info
Product images
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