Recombinant Human JAM-A / F11R Protein (His tag) 100µg

• Catalog number
  PKSH031771-100µg
• Price
  Please ask
• Size
  100µg

• Synonym
  CD321;JAM;JAM1;JAMA;JCAM;KAT;PAM-1
• Activity
  Measured by the ability of the immobilized protein to support the adhesion of Jurkat human acute T cell leukemia cells.When 8 x 104 cells/well are added to JAM-A-Fc coated plates (2.5μg/mL, 100 μL/well)in the presence of 20 ng/mL PMA, approximately 30-40% will adhere after 30 minutes at 37℃.
• Sequence
  Met 1-Ala 242
• Fusion tag
  C-His
• Accession
  NP_058642.1
• Expressed Host
  HEK293 Cells
• Shipping
  In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
• Purity
  ＞97 % as determined by SDS-PAGE
• Endotoxin
  ＜1.0 EU per µg as determined by the LAL method
• Stability and Storage
  Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Mol Mass
  25 kDa
• AP Mol Mass
  28-32 kDa
• Formulation
  Lyophilized from sterile PBS, pH 7.4
• Reconstitution
  Please refer to it for detailed information.
• Background
  Junctional adhesion molecule-A (JAM-A), also known as F11 receptor (F11R) or Cluster of Differentiation 321 (CD321), is a transmembrane protein expressed at tight junctions of epithelial and endothelial cells, as well as on circulating leukocytes. JAM-A protein serves as a serotype-independent receptor for mammalian orthoreoviruses (reoviruses). It is also a ligand for the integrin LFA1, involves in leukocyte transmigration. As a cell adhesion molecule of the immunoglobulin superfamily, JAM-A protein involves in platelet adhesion, secretion and aggregation, and plays a crucial role in inflammatory thrombosis and atherosclerosis. In addition, it may be a potential therapeutic target for breast cancer.
• Product URL
• PDF URL
• Conjugation
  histidine
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  JAM-A   F11R   Protein   His   tag   100µg  
• Gene symbol
  F11R, JAM2, JAM3, HLA-A, IGHV5-10-1, CIDEA, RPA1, CDC37P1, OR1Q1
• Short name
  Recombinant JAM-A / F11R Protein (His tag) 100µg
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
• Label
  His
• Species
  Human, Humans
• Alternative name
  Rec. H. sapiens JAM-A / F11 receptor Protein (histidine detection labelled) 100µg
• Alternative technique
  rec
• Alternative to gene target
  F11 receptor, F11R and IDBG-104131 and ENSG00000158769 and 50848, protein binding, Cell surfaces, F11r and IDBG-204606 and ENSMUSG00000038235 and 16456, F11R and IDBG-630243 and ENSBTAG00000017846 and 281258

Gene info

• Identity
  HGNC:14685
• Gene
  F11R
• Long gene name
  F11 receptor
• Synonyms gene
  • JAM1
• Synonyms gene name
  • junctional adhesion molecule 1
• Synonyms
  • PAM-1
  • JCAM
  • JAM-1
  • JAM-A
  • JAMA
  • CD321
• GenBank acession
  • AF111713
• Locus
  1q23.3
• Discovery year
  2001-04-10
• Entrez gene record
  50848
• Pubmed identfication
  • 10395639
  • 7646439
• RefSeq identity
  • NM_016946
• Classification
  • Ig-like cell adhesion molecule family
  • V-set domain containing
  • CD molecules
• VEGA ID
  OTTHUMG00000028602

Gene info

• Identity
  HGNC:14686
• Gene
  JAM2
• Long gene name
  junctional adhesion molecule 2
• Synonyms gene
  • C21orf43
• Synonyms
  • VE-JAM
  • JAM-B
  • JAMB
  • CD322
• GenBank acession
  • AF255910
• Locus
  21q21.3
• Discovery year
  2001-04-25
• Entrez gene record
  58494
• Pubmed identfication
  • 10779521
  • 10945976
• Classification
  • CD molecules
  • Ig-like cell adhesion molecule family
  • I-set domain containing
  • V-set domain containing
• VEGA ID
  OTTHUMG00000078441

Gene info

• Identity
  HGNC:15532
• Gene
  JAM3
• Long gene name
  junctional adhesion molecule 3
• Synonyms
  • JAM-C
  • JAMC
• GenBank acession
  • AF356518
• Locus
  11q25
• Discovery year
  2001-04-26
• Entrez gene record
  83700
• RefSeq identity
  • NM_032801
• Classification
  • Small nucleolar RNA protein coding host genes
  • Ig-like cell adhesion molecule family
  • V-set domain containing
• VEGA ID
  OTTHUMG00000167130

Gene info

• Identity
  HGNC:4931
• Gene
  HLA-A
• Long gene name
  major histocompatibility complex, class I, A
• GenBank acession
  • D32129
• Locus
  6p22.1
• Discovery year
  2001-06-22
• Entrez gene record
  3105
• Pubmed identfication
  • 8838351
• RefSeq identity
  • NM_002116
• Classification
  • C1-set domain containing
  • Histocompatibility complex
• VEGA ID
  OTTHUMG00000130501
• Locus Specific Databases
  • IMGT/HLA Database

Gene info

• Identity
  HGNC:5661
• Gene
  IGHV5-10-1
• Long gene name
  immunoglobulin heavy variable 5-10-1
• Synonyms gene
  • IGHV5-A
• Synonyms gene name
  • immunoglobulin heavy variable 5-A (provisional, gene/pseudogene)
  • immunoglobulin heavy variable 5-A (provisional)
• Synonyms
  • IGHV5-a
• GenBank acession
  • X92227
• Locus
  14q32.33
• Discovery year
  2000-04-04
• Entrez gene record
  28386
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000191143

Gene info

• Identity
  HGNC:1976
• Gene
  CIDEA
• Long gene name
  cell death inducing DFFA like effector a
• Synonyms gene name
  • cell death-inducing DFFA-like effector a
• Synonyms
  • CIDE-A
• GenBank acession
  • AF041378
• Locus
  18p11.21
• Discovery year
  1998-07-15
• Entrez gene record
  1149
• Pubmed identfication
  • 9564035
  • 18509062
• RefSeq identity
  • NM_001279
• VEGA ID
  OTTHUMG00000131691

Gene info

• Identity
  HGNC:10289
• Gene
  RPA1
• Long gene name
  replication protein A1
• Synonyms gene name
  • replication protein A1 (70kD)
  • replication protein A1, 70kDa
• Synonyms
  • REPA1
  • RPA70
  • HSSB
  • RF-A
  • RP-A
• GenBank acession
  • M63488
• Locus
  17p13.3
• Discovery year
  1993-12-14
• Entrez gene record
  6117
• Pubmed identfication
  • 8454588
• RefSeq identity
  • NM_002945
• Classification
  • Nucleotide excision repair
• VEGA ID
  OTTHUMG00000090579

Gene info

• Identity
  HGNC:34406
• Gene
  CDC37P1
• Long gene name
  cell division cycle 37 pseudogene 1
• Synonyms gene name
  • cell division cycle 37 homolog (S. cerevisiae) pseudogene 1
• Synonyms
  • A-761H5.2
• Locus
  16p11.2
• Discovery year
  2009-01-29
• Entrez gene record
  390688
• Pubmed identfication
  • 15616553
• RefSeq identity
  • NG_009463
• VEGA ID
  OTTHUMG00000175739

Gene info

• Identity
  HGNC:8223
• Gene
  OR1Q1
• Long gene name
  olfactory receptor family 1 subfamily Q member 1
• Synonyms gene
  • OR1Q2
  • OR1Q3
• Synonyms gene name
  • olfactory receptor, family 1, subfamily Q, member 1
• Synonyms
  • OST226
  • OR9-A
  • HSTPCR106
  • OST226OR9-A
  • TPCR106
• Locus
  9q33.2
• Discovery year
  1999-12-09
• Entrez gene record
  158131
• Classification
  • Olfactory receptors, family 1
• VEGA ID
  OTTHUMG00000020615

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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