Interleukin 6 Receptor, soluble, Recombinant, Human (IL6-sR)

• Catalog number
  MBS650479
• Price
  Please ask
• Size
  0.01 mg

• Products_type
  Recombinant Protein
• Products_short_name
  [Interleukin 6 Receptor, soluble]
• Other_names
  [interleukin-6-receptor; Interleukin-6 receptor subunit alpha; interleukin-6 receptor subunit alpha; IL-6R 1; CD126 antigen; membrane glycoprotein 80; IL-6 receptor subunit alpha; interleukin 6 receptor; IL-6R 1; Membrane glycoprotein 80]
• Other_gene_names
  [IL6R; IL6R; IL6Q; gp80; CD126; IL6RA; IL6RQ; IL-6RA; IL-6R-1; IL-6 receptor subunit alpha; IL-6R subunit alpha; IL-6R-alpha; IL-6RA; gp80]
• Purity
  >95%
• Form
  20mM Tris HCl, pH 8.0 / 0.8M Urea / 50% Glycerol
• Concentration
  0.18mg/ml
• Storage_stability
  Store at -20°C.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Gene
  Interleukin 6 (IL-6) is an interleukin that acts as both a pro-inflammatory cytokine and an anti-inflammatory myokine. In humans, it is encoded by the IL6 gene. Recombinant, rec. E. coli interleukin-6 for cell culture or antibody production.
• Description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Interleukin   Receptor   soluble   IL6-sR  
• Gene symbol
  IL6-AS1, IL6, CEBPD
• Short name
  Interleukin 6 Receptor, soluble, Recombinant, (IL6-sR)
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  Interleukin 6 Receptor, soluble, Rec., H. sapiens (interleukin 6 (interferon, beta 2)-sR)
• Alternative technique
  rec
• Alternative to gene target
  interleukin 6 (interferon, beta 2), BSF2 and HGF and HSF and IFNB2 and IL-6, IL6 and IDBG-9462 and ENSG00000136244 and 3569, growth factor activity, Extracellular, Il6 and IDBG-144970 and ENSMUSG00000025746 and 16193, IL6 and IDBG-630280 and ENSBTAG00000014921 and 280826

Gene info

• Identity
  HGNC:40301
• Gene
  IL6-AS1
• Long gene name
  IL6 antisense RNA 1
• Locus
  7p15.3
• Discovery year
  2019-08-14
• Entrez gene record
  541472
• RefSeq identity
  • NR_131935
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:6018
• Gene
  IL6
• Long gene name
  interleukin 6
• Synonyms gene
  • IFNB2
• Synonyms gene name
  • interleukin 6 (interferon, beta 2)
• Synonyms
  • IL-6
  • BSF2
  • HGF
  • HSF
• Synonyms name
  • interferon, beta 2
• GenBank acession
  • M18403
• Locus
  7p15.3
• Discovery year
  1986-01-01
• Entrez gene record
  3569
• Pubmed identfication
  • 3294161
• RefSeq identity
  • NM_000600
• Classification
  • Interleukins
  • Interferons
  • Interleukin 6 type cytokine family
• VEGA ID
  OTTHUMG00000023178

Gene info

• Identity
  HGNC:1835
• Gene
  CEBPD
• Long gene name
  CCAAT enhancer binding protein delta
• Synonyms gene name
  • CCAAT/enhancer binding protein (C/EBP), delta
  • CCAAT/enhancer binding protein delta
• Synonyms
  • CRP3
  • CELF
  • C/EBP-delta
  • NF-IL6-beta
• Locus
  8q11.21
• Discovery year
  1992-06-24
• Entrez gene record
  1052
• Pubmed identfication
  • 1840554
  • 1884998
• RefSeq identity
  • NM_005195
• Classification
  • Basic leucine zipper proteins
  • CCAAT/enhancer binding proteins
• VEGA ID
  OTTHUMG00000162290

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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