Recombinant human DNA repair protein complementing XP-C cells

Similar name

DNA repair protein complementing XP-C cells
Other name

Recombinant Human DNA repair protein complementing XP-C cells Expressed in E.coli
Synonym

Recombinant DNA repair protein complementing XP-C cells
Little description

Our DNA repair protein complementing XP-C cells is a recombinant Human protein expressed in E.coli with His-SUMO-tag
Expression system

E.coli
Origin species

Human
Conjugation

His-SUMO-tag
Storage

For long term storage, keep the Recombinant human DNA repair protein complementing XP-C cells frozen at -20 or -80 degrees Celsius. Working aliquots can be stored at +4C for a few weeks. We recommend cycles of freezing and thawing to be avoided, as they will most certainly denaturate the polypeptide chains of the protein.
Shipping

The Human DNA repair protein complementing XP-C cells is shipped on ice packs.
Datasheet
Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Source

Recombinants or rec. proteins
Group

recombinants

Gene target

DNA repair protein complementing XP-C cells
Gene symbol

XPC-AS1, XPC, POLH, SMC4, PRKDC, MYB, PCK1, MAGEB2, MAGEB1, MKRN4P
Short name

Recombinant DNA repair protein complementing XP-C cells
Technique

Recombinant, dna, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. SAB advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
Species

Human, Humans
Alternative name

Human DNA repair protein complementing XP-C cells
Alternative technique

rec
Tissue

cells

Identity

HGNC:14013
Gene

SMC4
Long gene name

structural maintenance of chromosomes 4
Synonyms gene
- SMC4L1
Synonyms gene name
- SMC4 (structural maintenance of chromosomes 4, yeast)-like 1
- SMC4 structural maintenance of chromosomes 4-like 1 (yeast)
Synonyms
- hCAP-C
- CAP-C
GenBank acession
- AF092564
Locus

3q25.33
Discovery year

2001-02-22
Entrez gene record

10051
Pubmed identfication
- 9789013
- 10319587
Classification
- Structural maintenance of chromosomes proteins
- Condensin I subunits
- Condensin II subunits
- MicroRNA protein coding host genes
VEGA ID

OTTHUMG00000159006

Identity

HGNC:6808
Gene

MAGEB1
Long gene name

MAGE family member B1
Synonyms gene name
- melanoma antigen family B1
Synonyms
- MAGEL1
- MAGE-Xp
- DAM10
- MGC9322
- CT3.1
Synonyms name
- DSS/AHC critical interval MAGE superfamily 10
- cancer/testis antigen family 3, member 1
Locus

Xp21.2
Discovery year

1997-08-15
Entrez gene record

4112
Pubmed identfication
- 7761436
- 9441743
RefSeq identity
- NM_002363
Classification
- MAGE family
VEGA ID

OTTHUMG00000021322
Locus Specific Databases
- Global Variome shared LOVD

Identity

HGNC:7115
Gene

MKRN4P
Long gene name

makorin ring finger protein 4, pseudogene
Synonyms gene
- ZNF127L1
- MKRN4
- MKRNP5
Synonyms gene name
- makorin, ring finger protein, 4
- makorin ring finger protein pseudogene 5
Synonyms
- ZNF-Xp
- RNF64
GenBank acession
- U41315
Locus

Xp11.4
Discovery year

1992-11-06
Entrez gene record

7682
RefSeq identity
- NG_004713
Classification
- Ring finger proteins
VEGA ID

OTTHUMG00000024109

Name

Targeted Gene Repair
Concept

Scope note: A technique which uses synthetic oligonucleotides to direct the cell's inherent DNA repair system to correct a mutation at a specific site in an episome or chromosome.
Tree numbers
- E02.095.301.500
- E05.393.420.301.500
- E05.393.420.601.575.500
Qualifiers

legislation & jurisprudence, ethics, mortality, psychology, trends, veterinary, history, classification, economics, instrumentation, methods, nursing, standards, adverse effects, statistics & numerical data