Recombinant Human COL6A3 / Collagen-VI Protein 100µg

• Catalog number
  PKSH030495-100µg
• Price
  Please ask
• Size
  100µg

• Synonym
  COL6A3;Collagen-VI
• Activity
  NA
• Sequence
  Thr3101-Thr3177
• Fusion tag
  NA
• Accession
  NP_004360.2
• Expressed Host
  HEK293 Cells
• Shipping
  In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
• Purity
  > 95 % as determined by SDS-PAGE.
• Endotoxin
  < 1.0 EU per μg protein as determined by the LAL method.
• Stability and Storage
  Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Mol Mass
  8.5 kDa
• AP Mol Mass
  8.5 kDa
• Formulation
  Lyophilized from sterile PBS, pH 7.4
• Reconstitution
  Please refer to it for detailed information.
• Background
  This gene encodes the alpha-3 chain, one of the three alpha chains of type VI collagen, a beaded filament collagen found in most connective tissues. The alpha-3 chain of type VI collagen is much larger than the alpha-1 and -2 chains. This difference in size is largely due to an increase in the number of subdomains, similar to von Willebrand Factor type A domains, that are found in the amino terminal globular domain of all the alpha chains. These domains have been shown to bind extracellular matrix proteins, an interaction that explains the importance of this collagen in organizing matrix components. Mutations in the type VI collagen genes are associated with Bethlem myopathy, a rare autosomal dominant proximal myopathy with early childhood onset. Mutations in this gene are also a cause of Ullrich congenital muscular dystrophy, also referred to as Ullrich scleroatonic muscular dystrophy, an autosomal recessive congenital myopathy that is more severe than Bethlem myopathy. Multiple transcript variants have been identified, but the full-length nature of only some of these variants has been described.
• Product URL
• PDF URL
• Gene
  Collagen Types in bones and muscles can be hydrolyzed and used in human grafts. ( Type II )
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  COL6A3   Collagen-VI   Protein   100µg  
• Gene symbol
  APOL6, B4GALT6, IGHV1-3, FUT6, MARCHF6, IGLVVI-25-1, IGLVVI-22-1, COL6A3
• Short name
  Recombinant COL6A3 / Collagen-VI Protein 100µg
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  Rec. H. sapiens collagen, classification VI, a 3 / Collagen-VI Protein 100µg
• Alternative technique
  rec
• Alternative to gene target
  collagen, type VI, alpha 3, COL6A3 and IDBG-84192 and ENSG00000163359 and 102723826,102725336,1293, protein binding, Extracellular, Col6a3 and IDBG-180058 and ENSMUSG00000048126 and 12835, COL6A3 and IDBG-642059 and ENSBTAG00000030190 and 530657

Gene info

• Identity
  HGNC:14870
• Gene
  APOL6
• Long gene name
  apolipoprotein L6
• Synonyms
  • APOL-VI
  • APOLVI
• GenBank acession
  • AY014879
• Locus
  22q12.3
• Discovery year
  2001-03-21
• Entrez gene record
  80830
• Pubmed identfication
  • 11374903
  • 15671246
• RefSeq identity
  • NM_030641
• Classification
  • Apolipoproteins
• VEGA ID
  OTTHUMG00000150615

Gene info

• Identity
  HGNC:929
• Gene
  B4GALT6
• Long gene name
  beta-1,4-galactosyltransferase 6
• Synonyms gene name
  • UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
• Synonyms
  • beta4GalT-VI
• Synonyms name
  • UDP-Gal:glucosylceramide beta-1,4-galactosyltransferase
• GenBank acession
  • AF038664
• Locus
  18q12.1
• Discovery year
  1999-03-15
• Entrez gene record
  9331
• Pubmed identfication
  • 9597550
  • 12180132
• RefSeq identity
  • NM_004775
• Classification
  • Beta 4-glycosyltransferases
• VEGA ID
  OTTHUMG00000131980

Gene info

• Identity
  HGNC:5552
• Gene
  IGHV1-3
• Long gene name
  immunoglobulin heavy variable 1-3
• Synonyms
  • VI-3B
• GenBank acession
  • X62109
• Locus
  14q32.33
• Discovery year
  2000-04-04
• Entrez gene record
  28473
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000152323

Gene info

• Identity
  HGNC:4017
• Gene
  FUT6
• Long gene name
  fucosyltransferase 6
• Synonyms
  • FT1A
  • FCT3A
  • FucT-VI
  • FLJ40754
• Synonyms name
  • alpha-(1,3)-fucosyltransferase
  • galactoside 3-L-fucosyltransferase
• Locus
  19p13.3
• Discovery year
  1993-04-15
• Entrez gene record
  2528
• Pubmed identfication
  • 1520296
  • 7782074
• RefSeq identity
  • NM_000150
• Classification
  • Fucosyltransferases
• VEGA ID
  OTTHUMG00000167335
• Locus Specific Databases
  • Blood Group Antigen Mutation Database

Gene info

• Identity
  HGNC:30550
• Gene
  MARCHF6
• Long gene name
  membrane associated ring-CH-type finger 6
• Synonyms gene
  • MARCH6
• Synonyms gene name
  • membrane-associated ring finger (C3HC4) 6
  • membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
• Synonyms
  • TEB4
  • MARCH-VI
  • RNF176
• GenBank acession
  • AB011169
• Locus
  5p15.2
• Discovery year
  2005-01-26
• Entrez gene record
  10299
• Pubmed identfication
  • 14722266
• RefSeq identity
  • NM_005885
• Classification
  • Membrane associated ring-CH-type fingers
  • Ring finger proteins
• VEGA ID
  OTTHUMG00000162027

Gene info

• Identity
  HGNC:15690
• Gene
  IGLVVI-25-1
• Long gene name
  immunoglobulin lambda variable (VI)-25-1 (pseudogene)
• Synonyms gene name
  • immunoglobulin lambda variable (VI)-25-1
  • immunoglobulin lambda variable (VI)-25-1 pseudogene
• Synonyms
  • IGLV(VI)-25-1
• GenBank acession
  • D86994
• Locus
  22q11.22
• Discovery year
  2001-05-15
• Entrez gene record
  84090
• RefSeq identity
  • NG_000002
• Classification
  • Immunoglobulin lambda locus at 22q11.2
• VEGA ID
  OTTHUMG00000151586

Gene info

• Identity
  HGNC:15689
• Gene
  IGLVVI-22-1
• Long gene name
  immunoglobulin lambda variable (VI)-22-1 (pseudogene)
• Synonyms gene name
  • immunoglobulin lambda variable (VI)-22-1
  • immunoglobulin lambda variable (VI)-22-1 pseudogene
• Synonyms
  • IGLV(VI)-22-1
• GenBank acession
  • X71351
• Locus
  22q11.22
• Discovery year
  2001-05-15
• Entrez gene record
  84091
• RefSeq identity
  • NG_000002
• Classification
  • Immunoglobulin lambda locus at 22q11.2
• VEGA ID
  OTTHUMG00000151219

Gene info

• Identity
  HGNC:2213
• Gene
  COL6A3
• Long gene name
  collagen type VI alpha 3 chain
• Synonyms gene name
  • collagen, type VI, alpha 3
• GenBank acession
  • X52022
• Locus
  2q37.3
• Discovery year
  2001-06-22
• Entrez gene record
  1293
• Pubmed identfication
  • 1339440
  • 11992252
  • 23869615
• RefSeq identity
  • NM_004369
• Classification
  • Collagens
• VEGA ID
  OTTHUMG00000150020
• Locus Specific Databases
  • Leiden Muscular Dystrophy Pages
  • Leiden Muscular Dystrophy pages
  • LRG_473

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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