Recombinant Human CNDP2 / CPGL / PEPA Protein (His tag) 20µg
-
Catalog number
PKSH031810-20µg
-
Price
Please ask
-
Size
20µg
-
-
Synonym
CN2;CPGL;HEL-S-13;HsT2298;PEPA
-
Activity
NA
-
Sequence
Met 1-Asp 475
-
Fusion tag
C-His
-
Accession
CAC69883.1
-
Expressed Host
Baculovirus-Insect Cells
-
Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
-
Purity
＞94 % as determined by SDS-PAGE
-
Endotoxin
＜1.0 EU per µg as determined by the LAL method
-
Stability and Storage
Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Mol Mass
54.2 kDa
-
AP Mol Mass
54.2 kDa
-
Formulation
Lyophilized from sterile 50mM Tris, 100mM NaCl, 0.5mM PMSF, pH 8.0
-
Reconstitution
Please refer to it for detailed information.
-
Background
Cytosolic non-specific dipeptidase, also known as CNDP dipeptidase 2, Glutamate carboxypeptidase-like protein 1, Peptidase A, CNDP2 and CN2, is a cytoplasm protein which belongs to the peptidase M20A family. CNDP2 / CPGL is a cytosolic enzyme that can hydrolyze carnosine to yield l-histidine and beta-alanine. CNDP2 / CPGL hydrolyzes a variety of dipeptides including L-carnosine but has a strong preference for Cys-Gly. It may be play a role as tumor suppressor in hepatocellular carcinoma (HCC) cells. Isoform 1 of CNDP2 / CPGL is ubiquitously expressed with higher levels in kidney and liver (at protein level). Isoform 2 of CNDP2 / CPGL is expressed in fetal tissues, it is only expressed in adult liver and placental tissues. CNDP2 / CPGL is highly expressed in the histaminergic neurons in the tuberomammillary nucleus, implying that it may supply histidine to histaminergic neurons for histamine synthesis.
-
-
-
Conjugation
histidine
-
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
-
Source
Recombinants or rec. proteins
-
Group
recombinants
-
Gene target
-
Gene symbol
CNDP2
-
Short name
Recombinant CNDP2 / CPGL / PEPA Protein (His tag) 20µg
-
Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
-
Label
His
-
Species
Human, Humans
-
Alternative name
Rec. H. sapiens CNDP2 / CPGL / PEPA Protein (histidine detection labelled) 20µg
-
Alternative technique
rec
-
Gene info
-
Identity
-
Gene
-
Long gene name
carnosine dipeptidase 2
-
Synonyms gene
-
Synonyms gene name
- peptidase A
- CNDP dipeptidase 2 (metallopeptidase M20 family)
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year
2004-04-14
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
-
VEGA ID
MeSH Data
-
Name
-
Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
-
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
-
Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
Similar products
