Recombinant Human CMPK1 Protein (His tag)

• Catalog number
  PKSH030319-50µg
• Price
  Please ask
• Size
  50µg

• Synonym
  CK;CMK;CMPK;UMK;UMP-CMPK;UMPK
• Activity
  NA
• Sequence
  Met1-Gly196
• Fusion tag
  N-His
• Accession
  P30085
• Expressed Host
  Baculovirus-Insect Cells
• Shipping
  Kinases are highly recommended to be shipped at frozen temperature with blue ice or dry ice.Shipment made at ambient temperature may seriously affect the activity of the ordered products.
• Purity
  ＞95 % as determined by SDS-PAGE
• Endotoxin
  ＜1.0 EU per µg as determined by the LAL method
• Stability and Storage
  Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Mol Mass
  24.5 kDa
• AP Mol Mass
  27 kDa
• Formulation
  Supplied as sterile 20mM Tris, 500mM Nacl, pH 7.4, 10% glycerol
• Background
  CMPK1 plays a key role in the maintenance of pyrimidine nucleotide pool profile and for the metabolism of pyrimidine analogs in cells. It catalyzes the phosphoryl transfer from ATP to UMP, CMP, and deoxy-CMP (dCMP), resulting in the formation of ADP and the corresponding nucleoside diphosphate. CMPK1 also has a significant role in the activation of pyrimidine analogs, which are clinically useful anti-cancer and anti-viral drugs. In the meanwhile, CMPK1 functions in cellular nucleic acid biosynthesis.
• Technical data
• Conjugation
  histidine
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  CMPK1   Protein   His   tag  
• Gene symbol
  CMPK1
• Short name
  Recombinant CMPK1 Protein (His tag)
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
• Label
  His
• Species
  Human, Humans
• Alternative name
  Rec. H. sapiens CMPK1 Protein (histidine detection labelled)
• Alternative technique
  rec

Gene info

• Identity
  HGNC:18170
• Gene
  CMPK1
• Long gene name
  cytidine/uridine monophosphate kinase 1
• Synonyms gene
  • CMPK
• Synonyms gene name
  • cytidylate kinase
  • cytidine monophosphate (UMP-CMP) kinase 1, cytosolic
• Synonyms
  • UMP-CMPK
• Synonyms name
  • UMP-CMP kinase
  • Cytidine monophosphate kinase
  • UMP/CMP kinase
• GenBank acession
  • AF070416
• Locus
  1p33
• Discovery year
  2005-05-10
• Entrez gene record
  51727
• Pubmed identfication
  • 10462544
• RefSeq identity
  • NM_016308
• VEGA ID
  OTTHUMG00000007849

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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